CST3 Monoclonal Antibody

Datasheet
Code CSB-MA061901A0m
Product Type Monoclonal Antibody
Size US$350Purchase it in Cusabio online store
(Shop online in the US. Customers outside the US,
please order from local distributors.)
Image
  • Immunohistochemical of paraffin-embedded human prostate tissue using CSB-MA061901A0m at dilution of 1:200

  • Immunohistochemical of paraffin-embedded human kidney tissue using CSB-MA061901A0m at dilution of 1:200

Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Recombinant Human Cystatin C protein
Raised in mouse
Species Reactivity Human
Specificity CSB-MA061961A0m is specific for Human Cystatin C denatured and native forms
Tested Applications ELISA,IHC;Recommended dilution:IHC:1:50-1:500
Relevance Defects in CST3 are the cause of amyloidosis type 6 (AMYL6) [MIM:105150]; also known as hereditary cerebral hemorrhage with amyloidosis (HCHWA), cerebral amyloid angiopathy (CAA) or cerebroarterial amyloidosis Icelandic type. AMYL6 is a hereditary generalized amyloidosis due to cystatin C amyloid deposition. Cystatin C amyloid accumulates in the walls of arteries, arterioles, and sometimes capillaries and veins of the brain, and in various organs including lymphoid tissue, spleen, salivary glands, and seminal vesicles. Amyloid deposition in the cerebral vessels results in cerebral amyloid angiopathy, cerebral hemorrhage and premature stroke. Cystatin C levels in the cerebrospinal fluid are abnormally low.Genetic variations in CST3 are associated with age-related macular degeneration type 11 (ARMD11) [MIM:611953]. ARMD is a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane.
Form liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%,Protein G purified
Isotype IgG2b
Clonality monoclonal
Alias CysC,Cystatin-3,Gamma-trace,Neuroendocrine basic polypeptide,Post-gamma-globulin
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Clone No. 3A1B7
Still Have Questions? Leave a Message or Start an on-line Chat

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.