Code | CSB-MA731035A0m |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
IHC | 1:50-1:200 |
FC | 1:50-1:200 |
The MERTNL monoclonal antibody is generated using the recombinant human MERTNL protein (46-311aa) as the immunogen to immunize mice. The B cells are isolated from the immunized mice and are fused with myeloma cells to produce hybridoma cells, which are screened to select the hybridoma cell line that secretes the MERTNL antibody. The MERTNL antibody-generating hybridoma cell line is injected into the mouse abdominal cavity. The MERTNL monoclonal antibody is purified and obtained from the mouse ascites using protein A affinity chromatography with a purity of over 95%. It is an unconjugated IgG2a antibody that recognizes human MERTNL protein and is suitable for use in ELISA, IHC and FC applications.
MERTNL is a protein that acts as a ligand for the MER receptor tyrosine kinase, which is a member of the TAM family of receptor tyrosine kinases that play important roles in the regulation of immune responses, inflammation, and homeostasis. MERTNL is primarily expressed in the placenta and has been implicated in regulating the development and function of the placenta.
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