Recombinant Human GDNF family receptor alpha-1(GFRA1) (Active)

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Code CSB-AP005691HU
Product Type Other
Size $52Purchase it in Cusabio online store
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Uniprot No. P56159
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Storage Buffer Lyophilized from a 0.2 μm filtered 20 mM PB, 150 mM NaCl, pH 7.2
Alias GDNF Family Receptor Alpha-1; GDNF Receptor Alpha-1; GDNFR-Alpha-1; GFR-Alpha-1; RET Ligand 1; TGF-Beta-Related Neurotrophic Factor Receptor 1; GFRA1; GDNFRA; RETL1; TRNR1
Species Homo sapiens (Human)
Biological_Activity The ED50 as determined by its ability to bind Human GDNF in functional ELISA is less than 10 ug/ml.
Purity Greater than 90% as determined by SDS-PAGE.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence DRLDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQSLQGNDLLEDSPYEPVNSRLSDIFRVVPFISDVFQQVEHIPKGNNCLDAAKACNLDDICKKYRSAYITPCTTSVSNDVCNRRKCHKALRQFFDKVPAKHSYGMLFCSCRDIACTERRRQTIVPVCSYEEREKPNCLNLQDSCKTNYICRSRLADFFTNCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPNYIDSSSLSVAPWCDCSNSGNDLEECLKFLNFFKDNTCLKNAIQAFGNGSDVTVWQPAFPVQTTTATTTTALRVKNKPLGPAGSENEIPTHVLPPCANLQAQKLKSNVSGNTHLCISNGNYEKEGLGASS
Research Area Neuroscience
Source Mammalian cell
Gene Names GFRA1
Expression Region 25-429aa
Tag Info C-terminal 6xHis-tagged
Mol. Weight 46.28 kDa
Protein Description Full Length of Mature Protein
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Function Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity).
Subcellular Location Cell membrane, Lipid-anchor, GPI-anchor
Protein Families GDNFR family
Database Links

HGNC: 4243

OMIM: 601496

KEGG: hsa:2674

STRING: 9606.ENSP00000393725

UniGene: Hs.388347

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