Recombinant Poecilobdella viridis Hirudin(Active)

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Code CSB-AP000241PNX
Product Type Other
Size US$112Purchase it in Cusabio online store
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Uniprot No. P84590
Lead Time 5-10 business days
Image
Storage Buffer 0.2 μm filtered 20 mM PBS, pH 7.0, containing 2 % mannitol ,lyophilized
Species Poecilobdella viridis (Indian freshwater leech)
Biological_Activity The biological activity is determined by chromogenic assay, 1 unit is defined as the amount of Hirudin that neutralizes 1 unit of the WHO preparation 89/588 of thrombin. The specific activity is no less than 14,000 ATU/mg protein.
Purity >96% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence VVYTDCTESG QNLCLCEGSN VCGQGNKCIL GSDGEKNQCV TGEGTPGPQS HNDGDFEEPE EYL
Research Area Neuroscience?
Source Yeast
Expression Region 1-63aa
Tag Info Tag-Free
Mol. Weight 6.7 kDa
Protein Description Full Length
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Function Hirudin is a potent thrombin-specific protease inhibitor. It forms a stable non-covalent complex with alpha-thrombin, thereby abolishing its ability to cleave fibrinogen.
Subcellular Location Secreted
Protein Families Protease inhibitor I14 (hirudin) family

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