AASDHPPT Antibody

Code CSB-PA648080
Size US$119
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  • Western Blot analysis of COLO205 cells using AASD-PPT Polyclonal Antibody

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Product Details

Uniprot No.
Target Names
AASDHPPT
Alternative Names
4' phosphopantetheinyl transferase antibody; 4'-phosphopantetheinyl transferase antibody; AASD PPT antibody; AASD-PPT antibody; AASDHPPT antibody; ADPPT_HUMAN antibody; Alpha aminoadipic semialdehyde dehydrogenase phosphopantetheinyl transferase antibody; Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase antibody; CGI 80 antibody; HAH P antibody; L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase antibody; LYS2 antibody; LYS5 antibody; LYS5 ortholog antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the N-terminal region of Human AASD-PPT.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'-phosphopantetheine moiety from coenzyme A, regardless of whether the CoA is presented in the free thiol form or as an acetyl thioester, to a serine residue of a broad range of acceptors including the acyl carrier domain of FASN.
Gene References into Functions
  1. Our study identifies human PPT as the FDH-modifying enzyme and supports the hypothesis that mammals utilize a single enzyme for all phosphopantetheinylation reactions. PMID: 19933275
  2. humans appear to utilize a single, broad specificity enzyme, 4'-phosphopantetheine transferase, for all posttranslational 4'-phosphopantetheinylation reactions PMID: 12815048
Subcellular Location
Cytoplasm, cytosol.
Protein Families
P-Pant transferase superfamily, AcpS family
Tissue Specificity
Detected in heart, skeletal muscle, placenta, testis, brain, pancreas, liver and kidney.
Database Links

HGNC: 14235

OMIM: 607756

KEGG: hsa:60496

STRING: 9606.ENSP00000278618

UniGene: Hs.524009

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