ABCA13 Antibody

Code CSB-PA294593
Size US$297 How to order?
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  • Immunofluorescence analysis of A549 cells, using ABCA13 antibody.
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) ABCA13 Polyclonal antibody
Uniprot No. Q86UQ4
Target Names ABCA13
Alternative Names Abca13 antibody; ABCAD_HUMAN antibody; ATP-binding cassette sub-family A member 13 antibody; FLJ33876 antibody; FLJ33951 antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Synthesized peptide derived from internal of Human ABCA13.
Immunogen Species Homo sapiens (Human)
Clonality Polyclonal
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration It differs from different batches. Please contact us to confirm it.
Form Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications ELISA,IF
Recommended Dilution
Application Recommended Dilution
IF 1:100-1:500
Protocols ELISA Protocol
Immunofluorescence (IF) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May mediate the cholesterol and gangliosides transport from the plasma membrane to intracellular vesicles in an ATP hydrolysis dependent manner, thus playing a role in their internalization by endocytic retrograde transport and may also participate in the endocytosis of synaptic vesicle in cortical neurons.
Gene References into Functions
  1. ABCA13 gene may contain overlapping common genetic risk factors for both major depressive disorder and schizophrenia in the Han Chinese population. PMID: 27712136
  2. Rare missense variants within a single gene, abca13, form yin yang haplotypes. PMID: 25898927
  3. The results of this study demonstrated that common genetic variants at ABCA13 are unlikely to be related to the pathogenesis of schizophrenia in the Han Chinese population. PMID: 23910238
  4. No copy number variation including ABCA13 was identified in schizophrenia, bipolar disorder, or major depressive disorder samples, nor in the controls. PMID: 23250005
  5. An alternative human ABCA13 transcript and protein. PMID: 23266639
  6. ABCA13 is a candidate gene in schizophrenia, bipolar disorder, and depression PMID: 19944402
  7. Description of a new gene that maps to chromosome 7. PMID: 12697998

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Subcellular Location Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein Families ABC transporter superfamily
Tissue Specificity Significantly expressed in the bone marrow, trachea, testis, thyroid and lung as well as in skin fibroblasts.
Database Links

HGNC: 14638

OMIM: 607807

KEGG: hsa:154664

STRING: 9606.ENSP00000411096

UniGene: Hs.226568

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