ABCA13 Antibody

Code CSB-PA007525
Size US$100
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Product Details

Uniprot No.
Target Names
ABCA13
Alternative Names
Abca13 antibody; ABCAD_HUMAN antibody; ATP-binding cassette sub-family A member 13 antibody; FLJ33876 antibody; FLJ33951 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human ABCA13.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
IF, ELISA
Recommended Dilution
Application Recommended Dilution
IF 1:200-1:1000
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May mediate the cholesterol and gangliosides transport from the plasma membrane to intracellular vesicles in an ATP hydrolysis dependent manner, thus playing a role in their internalization by endocytic retrograde transport and may also participate in the endocytosis of synaptic vesicle in cortical neurons.
Gene References into Functions
  1. ABCA13 gene may contain overlapping common genetic risk factors for both major depressive disorder and schizophrenia in the Han Chinese population. PMID: 27712136
  2. Rare missense variants within a single gene, abca13, form yin yang haplotypes. PMID: 25898927
  3. The results of this study demonstrated that common genetic variants at ABCA13 are unlikely to be related to the pathogenesis of schizophrenia in the Han Chinese population. PMID: 23910238
  4. No copy number variation including ABCA13 was identified in schizophrenia, bipolar disorder, or major depressive disorder samples, nor in the controls. PMID: 23250005
  5. An alternative human ABCA13 transcript and protein. PMID: 23266639
  6. ABCA13 is a candidate gene in schizophrenia, bipolar disorder, and depression PMID: 19944402
  7. Description of a new gene that maps to chromosome 7. PMID: 12697998

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Subcellular Location
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein Families
ABC transporter superfamily
Tissue Specificity
Significantly expressed in the bone marrow, trachea, testis, thyroid and lung as well as in skin fibroblasts.
Database Links

HGNC: 14638

OMIM: 607807

KEGG: hsa:154664

STRING: 9606.ENSP00000411096

UniGene: Hs.226568

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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