ABCF1 Antibody

Code CSB-PA261772
Size US$299 How to order?
Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA261772(ABCF1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA261772(ABCF1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details

Uniprot No. Q8NE71
Target Names ABCF1
Alternative Names ABC27 antibody; ABC50 antibody; ABCF1 antibody; ABCF1_HUMAN antibody; ATP binding cassette 50 (TNF alpha stimulated) antibody; ATP binding cassette 50 antibody; ATP binding cassette sub family F member 1 antibody; ATP binding cassette; sub family F (GCN20); member 1 antibody; ATP-binding cassette 50 antibody; ATP-binding cassette sub-family F member 1 antibody; AU041969 antibody; D17Wsu166e antibody; EST123147 antibody; GCN20 antibody; TNF alpha stimulated ABC protein antibody; TNF-alpha-stimulated ABC protein antibody; TNFalpha inducible ATP binding protein antibody; wu:fb79c06 antibody; wu:fc39a05 antibody; wu:fj94a08 antibody; zgc:85667 antibody
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Fusion protein of Human ABCF1
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Isotype IgG
Purification Method Antigen affinity purification
Concentration It differs from different batches. Please contact us to confirm it.
Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form Liquid
Tested Applications ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:10000
IHC 1:50-1:200
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis.
Gene References into Functions
  1. The high copy number variant in the ABCF1 gene was the strongest risk factor for gout. PMID: 28405828
  2. ABCF1 extrinsically regulates retinal pigment epithelial cell phagocytosis of shed photoreceptor outer segments. PMID: 25904329
  3. Elevated microRNA-23a Expression Enhances the Chemoresistance of Colorectal Cancer Cells with Microsatellite Instability to 5-Fluorouracil by Directly Targeting ABCF1 PMID: 25929864
  4. expression of ABC50 mutants, which cannot hydrolyse ATP, decreases general translation and relaxes the discrimination against the use of non-AUG codons at translation start sites. PMID: 25597744
  5. A rare copy number variation of the ABCF1 gene was detected among dengue patients from Malaysia. PMID: 24634119
  6. The results suggested that SNPs at PRR3 and ABCF1 genes and the haplotype composed by SNPs at GNL1 and PRR3 between the HLA-A and HLA-C genes tended to predict Graves ophthalmology in a gender-dependent manner in patients with Graves disease in Taiwan. PMID: 24908204
  7. ABCF1 showed a significant increase in expression after escitalopram treatment. PMID: 23719290
  8. ABCF1 is a critical protein that associates with viral double-stranded DNA. PMID: 23263557
  9. The two critical HLA regions for susceptibility to autoimmune pancreatitis are limited to the HLA-DRB1*0405-DQB1*0401 in the class II and the ABCF1in the class I regions. PMID: 17119950
  10. ABC50 N-terminal region interacts with eukaryotic initiation factor eIF2 and is a target for regulatory phosphorylation by CK2 PMID: 17894550
  11. ABC50 plays a key role in translation initiation and has functions that are distinct from those of other non-membrane ABC proteins. PMID: 19570978

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Subcellular Location [Isoform 2]: Cytoplasm. Nucleus, nucleoplasm. Nucleus envelope.
Protein Families ABC transporter superfamily, ABCF family, EF3 subfamily
Tissue Specificity Ubiquitous.
Database Links

HGNC: 70

OMIM: 603429

KEGG: hsa:23

STRING: 9606.ENSP00000313603

UniGene: Hs.655285

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Address
7505 Fannin St. Ste 610-312, Houston, TX 77054, USA
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