ABI3 Antibody, HRP conjugated

Code CSB-PA873732LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ABI3 Polyclonal antibody
Uniprot No.
Target Names
ABI3
Alternative Names
ABI3 antibody; NESHABI gene family member 3 antibody; New molecule including SH3 antibody; Nesh antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human ABI gene family member 3 protein (1-366AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May inhibit tumor metastasis. In vitro, reduces cell motility.
Gene References into Functions
  1. Low ABI3 expression is associated with thyroid carcinomas. PMID: 27036019
  2. Data show that protein-altering changes are in PLCG2, ABI3, and TREM2 genes highly expressed in microglia and highlight an immune-related protein-protein interaction network in Alzheimer's disease. PMID: 28714976
  3. Result links ABI3 to the pathogenesis and progression of some cancers and suggests that ABI3 or its pathway might have interest as therapeutic target. PMID: 21223585
  4. Forced expression of NESH suppresses motility and metastatic dissemination of malignant cells. PMID: 11956071
Subcellular Location
Cytoplasm. Note=Colocalizes with PAK2 at leading edge of cells.
Protein Families
ABI family
Tissue Specificity
Expressed in heart, lung, liver, pancreas, kidney, placenta and at low levels in brain and skeletal muscle.
Database Links

HGNC: 29859

OMIM: 606363

KEGG: hsa:51225

STRING: 9606.ENSP00000225941

UniGene: Hs.130719

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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