ACOX2 Antibody

Datasheet

Code	CSB-PA001173GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q99424

Target Names

ACOX2

Alternative Names

12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase antibody; 12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase antibody; 3 alpha 7 alpha 12 alpha trihydroxy 5 beta cholestanoyl CoA oxidase antibody; 3 alpha 7 alpha12 alpha trihydroxy 5 beta cholestanoyl CoA 24 hydroxylase antibody; 3-alpha antibody; 7-alpha antibody; ACOX 2 antibody; ACOX2 antibody; ACOX2_HUMAN antibody; Acyl CoA oxidase 2 antibody; Acyl Coenzyme A oxidase 2 antibody; Acyl Coenzyme A oxidase 2 branched chain antibody; Acyl coenzyme A oxidase 2 peroxisomal antibody; BCOX antibody; BRCACOX antibody; BRCOX antibody; Peroxisomal acyl-coenzyme A oxidase 2 antibody; Peroxisomal branched chain acyl CoA oxidase antibody; THCA CoA oxidase antibody; THCA-CoA oxidase antibody; THCCox antibody; Trihydroxycoprostanoyl CoA oxidase antibody; Trihydroxycoprostanoyl-CoA oxidase antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human ACOX2

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,IHC,IF

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids. Capable of oxidizing short as well as long chain 2-methyl branched fatty acids.

Gene References into Functions

We have identified by the first time in a young patient and his only sister a familiar genetic defect of an enzyme called ACOX2, which participates in the transformation of cholesterol into bile acids as a cause of increased serum transaminases in the absence of any other symptomatology. PMID: 27884763
Results found an ACOX2 variant present in a subset of human breast cancers and associated with improved outcome ER+ tumors suggesting it as a potential novel therapeutic biomarker in ER+ breast tumors. PMID: 26183823
Our results suggest that downregulation of ACOX2 is a shared risk factor for PE and CVD. PMID: 21343950

Involvement in disease

Congenital bile acid synthesis defect 6 (CBAS6)

Subcellular Location

Peroxisome.

Protein Families

Acyl-CoA oxidase family

Tissue Specificity

Present in all tissues tested: heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Most abundant in heart, liver and kidney.

Database Links

HGNC: 120

OMIM: 601641

KEGG: hsa:8309

STRING: 9606.ENSP00000307697

UniGene: Hs.444959

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

PPAR signaling pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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