ACSM3 Antibody

Code CSB-PA709601ESR2HU
Size US$166
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  • Western blot
    All lanes: Acyl-coenzyme A synthetase ACSM3, mitochondrial antibody at 10μg/ml
    Lane 1: 293T whole cell lysate
    Lane 2: Mouse kidney tissue
    Lane 3: A431 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 67, 50 kDa
    Observed band size: 67 kDa

  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA709601ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA709601ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ACSM3 Polyclonal antibody
Uniprot No.
Target Names
ACSM3
Alternative Names
ACSM3 antibody; ACSM3_HUMAN antibody; Acyl CoA synthetase medium chain family member 3 antibody; Acyl-CoA synthetase medium-chain family member 3 antibody; Acyl-coenzyme A synthetase ACSM3 antibody; Acyl-coenzyme A synthetase ACSM3; mitochondrial antibody; Butyrate CoA ligase 3 antibody; Butyrate--CoA ligase 3 antibody; Butyryl coenzyme A synthetase 3 antibody; Butyryl-coenzyme A synthetase 3 antibody; Middle chain acyl CoA synthetase 3 antibody; Middle-chain acyl-CoA synthetase 3 antibody; mitochondrial antibody; Protein SA homolog antibody; SA (rat hypertension associated) homolog antibody; SA antibody; SA hypertension associated homolog antibody; SA; rat; homolog of antibody; SAH antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Acyl-coenzyme A synthetase ACSM3, mitochondrial protein (387-586AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism. Capable of activating medium-chain fatty acids with a preference for isobutyrate among fatty acids with 2-6 carbon atoms.
Gene References into Functions
  1. Our data provide evidence for a differential expression and regulation of the ACSM3 gene in hepatocellular carcinoma PMID: 28390038
  2. Reduced ACSM3 is associated with impaired butyrate oxidation in ulcerative colitis. PMID: 21987487
  3. SA gene polymorphism may be associated with the renal prognosis of immunoglobulin A nephropathy through its effect on blood pressure. Sensitivity to this gene polymorphism increases in patients with renal injury. PMID: 12484505
  4. variation in SAH has a role in predisposition to overweight in hypertensives. PMID: 14567496
  5. confirms recent evidence that the SAH locus is associated with obesity-related hypertension PMID: 17278971
  6. family-based analyses of SA hypertension-associated homolog (SAH) gene variants did not reveal population stratification supporting an association of hypertension and gene variants PMID: 18192838
  7. We conclude that, in spite of its renal expression,1-3 the human SAH gene is unlikely to have an important role in renal sodium handling. PMID: 18519841
  8. SA hypertension-associated homolog(SAH) gene polymorphisms are associated with non-high-density lipoprotein cholesterol in postmenopausal women PMID: 19108963
  9. left ventricular mass index and mean wall thickness , two phenotypes that are jointly influenced by blood pressure and obesity, might be related to variation in the human SAH gene PMID: 19262474

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Subcellular Location
Mitochondrion. Mitochondrion matrix.
Protein Families
ATP-dependent AMP-binding enzyme family
Database Links

HGNC: 10522

OMIM: 145505

KEGG: hsa:6296

STRING: 9606.ENSP00000289416

UniGene: Hs.706754

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