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ACSM3 Antibody

Datasheet
Code CSB-PA709601ESR2HU
Size US$166
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  • Western Blotting(WB) - ACSM3 Antibody

    Western blot
    All lanes: Acyl-coenzyme A synthetase ACSM3, mitochondrial antibody at 10μg/ml
    Lane 1: 293T whole cell lysate
    Lane 2: Mouse kidney tissue
    Lane 3: A431 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 67, 50 kDa
    Observed band size: 67 kDa

  • Immunohistochemistry(IHC) 1- ACSM3 Antibody

    Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA709601ESR2HU at dilution of 1:100

  • Immunohistochemistry(IHC) 2- ACSM3 Antibody

    Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA709601ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ACSM3 Polyclonal antibody
Uniprot No.
Q53FZ2
Target Names
ACSM3
Alternative Names
ACSM3 antibody; ACSM3_HUMAN antibody; Acyl CoA synthetase medium chain family member 3 antibody; Acyl-CoA synthetase medium-chain family member 3 antibody; Acyl-coenzyme A synthetase ACSM3 antibody; Acyl-coenzyme A synthetase ACSM3; mitochondrial antibody; Butyrate CoA ligase 3 antibody; Butyrate--CoA ligase 3 antibody; Butyryl coenzyme A synthetase 3 antibody; Butyryl-coenzyme A synthetase 3 antibody; Middle chain acyl CoA synthetase 3 antibody; Middle-chain acyl-CoA synthetase 3 antibody; mitochondrial antibody; Protein SA homolog antibody; SA (rat hypertension associated) homolog antibody; SA antibody; SA hypertension associated homolog antibody; SA; rat; homolog of antibody; SAH antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Acyl-coenzyme A synthetase ACSM3, mitochondrial protein (387-586AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism. Capable of activating medium-chain fatty acids with a preference for isobutyrate among fatty acids with 2-6 carbon atoms.
Gene References into Functions
  1. Our data provide evidence for a differential expression and regulation of the ACSM3 gene in hepatocellular carcinoma PMID: 28390038
  2. Reduced ACSM3 is associated with impaired butyrate oxidation in ulcerative colitis. PMID: 21987487
  3. SA gene polymorphism may be associated with the renal prognosis of immunoglobulin A nephropathy through its effect on blood pressure. Sensitivity to this gene polymorphism increases in patients with renal injury. PMID: 12484505
  4. variation in SAH has a role in predisposition to overweight in hypertensives. PMID: 14567496
  5. confirms recent evidence that the SAH locus is associated with obesity-related hypertension PMID: 17278971
  6. family-based analyses of SA hypertension-associated homolog (SAH) gene variants did not reveal population stratification supporting an association of hypertension and gene variants PMID: 18192838
  7. We conclude that, in spite of its renal expression,1-3 the human SAH gene is unlikely to have an important role in renal sodium handling. PMID: 18519841
  8. SA hypertension-associated homolog(SAH) gene polymorphisms are associated with non-high-density lipoprotein cholesterol in postmenopausal women PMID: 19108963
  9. left ventricular mass index and mean wall thickness , two phenotypes that are jointly influenced by blood pressure and obesity, might be related to variation in the human SAH gene PMID: 19262474

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Subcellular Location
Mitochondrion. Mitochondrion matrix.
Protein Families
ATP-dependent AMP-binding enzyme family
Database Links

HGNC: 10522

OMIM: 145505

KEGG: hsa:6296

STRING: 9606.ENSP00000289416

UniGene: Hs.706754

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