ADAMTSL2 Antibody

Code CSB-PA105677
Size US$166
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  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: K562 cells, Jurkat cells, Primary antibody: CSB-PA105677(ADAMTSL2 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
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Product Details

Uniprot No.
Target Names
ADAMTSL2
Alternative Names
ADAMTS like 2 antibody; ADAMTS like protein 2 antibody; ADAMTS-like protein 2 antibody; ADAMTSL 2 antibody; ADAMTSL-2 antibody; ADAMTSL2 antibody; ATL2_HUMAN antibody; FLJ45164 antibody; KIAA0605 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human ADAMTSL2
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
WB 1:200-1:1000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. CpG-specific DNA methylation of ADAMTSL2 and BTN3A2 at rheumatoid arthritis diagnosis can serve as a marker of treatment response. PMID: 28447857
  2. Two compound heterozygous mutations were confirmed in the ADAMTSL2 gene of the patient with geleophysic dysplasia. PMID: 28917829
  3. A novel mutation in ADAMTSL2 (p. Gly421Ser) gene was identified in individuals with Ehlers-Danlos Syndrome. PMID: 26879370
  4. Two novel homozygous missense mutations in the ADAMTSL2 gene underlie geleophysic dysplasia in two consanguineous families from the United Arab Emirates. PMID: 24014090
  5. Molecular screening of ADAMTSL2 gene in 33 patients reveals the genetic heterogeneity of geleophysic dysplasia. PMID: 21415077
  6. These data suggest that ADAMTSL2 mutations may lead to a dysregulation of TGF-beta signaling and may be the underlying mechanism of geleophysic dysplasia. PMID: 18677313

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Involvement in disease
Geleophysic dysplasia 1 (GPHYSD1)
Subcellular Location
Secreted.
Database Links

HGNC: 14631

OMIM: 231050

KEGG: hsa:9719

STRING: 9606.ENSP00000346478

UniGene: Hs.522543

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