ADAMTSL2 Antibody

Code CSB-PA105677
Size US$166
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  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: K562 cells, Jurkat cells, Primary antibody: CSB-PA105677(ADAMTSL2 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
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Product Details

Uniprot No.
Target Names
ADAMTSL2
Alternative Names
ADAMTS like 2 antibody; ADAMTS like protein 2 antibody; ADAMTS-like protein 2 antibody; ADAMTSL 2 antibody; ADAMTSL-2 antibody; ADAMTSL2 antibody; ATL2_HUMAN antibody; FLJ45164 antibody; KIAA0605 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human ADAMTSL2
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
WB 1:200-1:1000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Gene References into Functions
  1. CpG-specific DNA methylation of ADAMTSL2 and BTN3A2 at rheumatoid arthritis diagnosis can serve as a marker of treatment response. PMID: 28447857
  2. Two compound heterozygous mutations were confirmed in the ADAMTSL2 gene of the patient with geleophysic dysplasia. PMID: 28917829
  3. A novel mutation in ADAMTSL2 (p. Gly421Ser) gene was identified in individuals with Ehlers-Danlos Syndrome. PMID: 26879370
  4. Two novel homozygous missense mutations in the ADAMTSL2 gene underlie geleophysic dysplasia in two consanguineous families from the United Arab Emirates. PMID: 24014090
  5. Molecular screening of ADAMTSL2 gene in 33 patients reveals the genetic heterogeneity of geleophysic dysplasia. PMID: 21415077
  6. These data suggest that ADAMTSL2 mutations may lead to a dysregulation of TGF-beta signaling and may be the underlying mechanism of geleophysic dysplasia. PMID: 18677313

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Involvement in disease
Geleophysic dysplasia 1 (GPHYSD1)
Subcellular Location
Secreted.
Database Links

HGNC: 14631

OMIM: 231050

KEGG: hsa:9719

STRING: 9606.ENSP00000346478

UniGene: Hs.522543

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