AEBP2 Antibody

Code CSB-PA156662
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA156662(AEBP2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA156662(AEBP2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
  • Gel: 12%SDS-PAGE, Lysate: 60 μg, Lane: Mouse liver tissue, Primary antibody: CSB-PA156662(AEBP2 Antibody) at dilution 1/225, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
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Product Details

Uniprot No.
Target Names
Alternative Names
AEBP2 antibody; Zinc finger protein AEBP2 antibody; Adipocyte enhancer-binding protein 2 antibody; AE-binding protein 2 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human AEBP2
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
WB 1:200-1:1000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Acts as an accessory subunit for the core Polycomb repressive complex 2 (PRC2), which mediates histone H3K27 (H3K27me3) trimethylation on chromatin leading to transcriptional repression of the affected target gene. Plays a role in nucleosome localization of the PRC2 complex.
Gene References into Functions
  1. retrotransposons as promoter, which display partial DNA methylation pattern of allelic- or non-allelic origin during different stages of development PMID: 25915901
  2. The first three-dimensional structure of the human polycomb repressive complex 2 complex bound to its cofactor AEBP2 has been presented. PMID: 23110252
Subcellular Location
Nucleus.
Protein Families
AEBP2/jing C2H2-type zinc-finger family
Database Links

HGNC: 24051

OMIM: 617934

KEGG: hsa:121536

STRING: 9606.ENSP00000381840

UniGene: Hs.126497

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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