AKAP3 Antibody

Datasheet

Code	CSB-PA001525GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

O75969

Target Names

AKAP3

Alternative Names

A kinase (PRKA) anchor protein 3 antibody; A-kinase anchor protein 110 kDa antibody; A-kinase anchor protein 3 antibody; AKAP 110 antibody; AKAP-3 antibody; AKAP110 antibody; Akap3 antibody; AKAP3_HUMAN antibody; Cancer/testis antigen 82 antibody; CT82 antibody; Fibrous sheath protein of 95 kDa antibody; Fibrousheathin 1 antibody; Fibrousheathin I antibody; Fibrousheathin-1 antibody; FSP95 antibody; PRKA3 antibody; protein kinase A binding protein AKAP 110 antibody; Protein kinase A-anchoring protein 3 antibody; SOB 1 antibody; SOB1 antibody; Sperm oocyte binding protein 1 antibody; Sperm oocyte-binding protein antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human AKAP3

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

May function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.

Gene References into Functions

AKAP3 correlates with triple negative status and disease free survival in breast cancer. PMID: 26458542
study reports the isolation of AKAP3 and CTp11 Cancer/testis antigens from hepatocellular carcinoma patient sera PMID: 22941507
CABYR variants form a complex not only with the scaffolding protein AKAP3 but also with another RII-like domain-containing protein in the sperm fibrous sheath. PMID: 21240291
evidence of tyrosine phosphorylation during sperm capacitation PMID: 12509440
In Cox multivariate analysis, AKAP3 mRNA expression was found to be a significant predictor of both overall and progression-free survival in patients with poorly differentiated tumors. PMID: 14618620
AKAP-3 demonstrates tumor-restricted expression and appears to be associated with worse overall survival. PMID: 16005946
AKAP3 is a novel target for protein S-nitrosylation in spermatozoa. PMID: 17683036

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Subcellular Location

Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Ribs of the fibrous sheath in the principal piece of the sperm tail. Dorsal margin of the acrosomal segment.

Protein Families

AKAP110 family

Tissue Specificity

Testis specific; only expressed in spermatids.

Database Links

HGNC: 373

OMIM: 604689

KEGG: hsa:10566

STRING: 9606.ENSP00000228850

UniGene: Hs.98397

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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