AKAP3 Antibody

Code CSB-PA001525GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
Alternative Names
A kinase (PRKA) anchor protein 3 antibody; A-kinase anchor protein 110 kDa antibody; A-kinase anchor protein 3 antibody; AKAP 110 antibody; AKAP-3 antibody; AKAP110 antibody; Akap3 antibody; AKAP3_HUMAN antibody; Cancer/testis antigen 82 antibody; CT82 antibody; Fibrous sheath protein of 95 kDa antibody; Fibrousheathin 1 antibody; Fibrousheathin I antibody; Fibrousheathin-1 antibody; FSP95 antibody; PRKA3 antibody; protein kinase A binding protein AKAP 110 antibody; Protein kinase A-anchoring protein 3 antibody; SOB 1 antibody; SOB1 antibody; Sperm oocyte binding protein 1 antibody; Sperm oocyte-binding protein antibody
Raised in
Species Reactivity
Human AKAP3
Immunogen Species
Homo sapiens (Human)
Purification Method
Antigen Affinity purified
It differs from different batches. Please contact us to confirm it.
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

May function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.
Gene References into Functions
  1. AKAP3 correlates with triple negative status and disease free survival in breast cancer. PMID: 26458542
  2. study reports the isolation of AKAP3 and CTp11 Cancer/testis antigens from hepatocellular carcinoma patient sera PMID: 22941507
  3. CABYR variants form a complex not only with the scaffolding protein AKAP3 but also with another RII-like domain-containing protein in the sperm fibrous sheath. PMID: 21240291
  4. evidence of tyrosine phosphorylation during sperm capacitation PMID: 12509440
  5. In Cox multivariate analysis, AKAP3 mRNA expression was found to be a significant predictor of both overall and progression-free survival in patients with poorly differentiated tumors. PMID: 14618620
  6. AKAP-3 demonstrates tumor-restricted expression and appears to be associated with worse overall survival. PMID: 16005946
  7. AKAP3 is a novel target for protein S-nitrosylation in spermatozoa. PMID: 17683036

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Subcellular Location
Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Ribs of the fibrous sheath in the principal piece of the sperm tail. Dorsal margin of the acrosomal segment.
Protein Families
AKAP110 family
Tissue Specificity
Testis specific; only expressed in spermatids.
Database Links

HGNC: 373

OMIM: 604689

KEGG: hsa:10566

STRING: 9606.ENSP00000228850

UniGene: Hs.98397

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