AKAP3 Antibody

Datasheet

Code	CSB-PA588403
Size	US$297
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Image	Immunofluorescence analysis of NIH/3T3 cells, using AKAP3 antibody.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) AKAP3 Polyclonal antibody

Uniprot No.

O75969

Target Names

AKAP3

Alternative Names

A kinase (PRKA) anchor protein 3 antibody; A-kinase anchor protein 110 kDa antibody; A-kinase anchor protein 3 antibody; AKAP 110 antibody; AKAP-3 antibody; AKAP110 antibody; Akap3 antibody; AKAP3_HUMAN antibody; Cancer/testis antigen 82 antibody; CT82 antibody; Fibrous sheath protein of 95 kDa antibody; Fibrousheathin 1 antibody; Fibrousheathin I antibody; Fibrousheathin-1 antibody; FSP95 antibody; PRKA3 antibody; protein kinase A binding protein AKAP 110 antibody; Protein kinase A-anchoring protein 3 antibody; SOB 1 antibody; SOB1 antibody; Sperm oocyte binding protein 1 antibody; Sperm oocyte-binding protein antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthesized peptide derived from internal of Human AKAP3.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,IF

Recommended Dilution

Application	Recommended Dilution
IF	1:100-1:500

Protocols

ELISA Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

May function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.

Gene References into Functions

AKAP3 correlates with triple negative status and disease free survival in breast cancer. PMID: 26458542
study reports the isolation of AKAP3 and CTp11 Cancer/testis antigens from hepatocellular carcinoma patient sera PMID: 22941507
CABYR variants form a complex not only with the scaffolding protein AKAP3 but also with another RII-like domain-containing protein in the sperm fibrous sheath. PMID: 21240291
evidence of tyrosine phosphorylation during sperm capacitation PMID: 12509440
In Cox multivariate analysis, AKAP3 mRNA expression was found to be a significant predictor of both overall and progression-free survival in patients with poorly differentiated tumors. PMID: 14618620
AKAP-3 demonstrates tumor-restricted expression and appears to be associated with worse overall survival. PMID: 16005946
AKAP3 is a novel target for protein S-nitrosylation in spermatozoa. PMID: 17683036

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Subcellular Location

Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Ribs of the fibrous sheath in the principal piece of the sperm tail. Dorsal margin of the acrosomal segment.

Protein Families

AKAP110 family

Tissue Specificity

Testis specific; only expressed in spermatids.

Database Links

HGNC: 373

OMIM: 604689

KEGG: hsa:10566

STRING: 9606.ENSP00000228850

UniGene: Hs.98397

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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