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ALG9 Antibody, FITC conjugated

Datasheet
Code CSB-PA867161LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ALG9 Polyclonal antibody
Uniprot No.
Q9H6U8
Target Names
ALG9
Alternative Names
ALG9 antibody; ALG9_HUMAN antibody; Alpha-1,2-mannosyltransferase ALG9 antibody; Asparagine-linked glycosylation protein 9 homolog antibody; Disrupted in bipolar disorder protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Alpha-1,2-mannosyltransferase ALG9 protein (434-618AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides.
Gene References into Functions
  1. ALG9 is upregulated in peripheral blood mononuclear cells of galactosaemia patients. PMID: 26733289
  2. Our study shows that some pathogenic variants in ALG9 can present as a lethal skeletal dysplasia with visceral malformations as the most severe phenotype PMID: 25966638
  3. Due to the ALG9 deficiency, cells accumulated the lipid-linked oligosaccharides Man(6)GlcNAc(2)-PP-dolichol and Man(8)GlcNAc(2)-PP-dolichol. PMID: 19451548
Involvement in disease
Congenital disorder of glycosylation 1L (CDG1L); Gillessen-Kaesbach-Nishimura syndrome (GIKANIS)
Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein Families
Glycosyltransferase 22 family
Tissue Specificity
Ubiquitously expressed; with highest levels in heart, liver and pancreas.
Database Links

HGNC: 15672

OMIM: 263210

KEGG: hsa:79796

STRING: 9606.ENSP00000435517

UniGene: Hs.745155

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