ALG9 Antibody

Code CSB-PA131441
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA131441(ALG9 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA131441(ALG9 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)
  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal liver tissue, Primary antibody: CSB-PA131441(ALG9 Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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Product Details

Uniprot No.
Target Names
ALG9
Alternative Names
ALG9 antibody; ALG9_HUMAN antibody; Alpha-1,2-mannosyltransferase ALG9 antibody; Asparagine-linked glycosylation protein 9 homolog antibody; Disrupted in bipolar disorder protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human ALG9
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
WB 1:200-1:1000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides.
Gene References into Functions
  1. ALG9 is upregulated in peripheral blood mononuclear cells of galactosaemia patients. PMID: 26733289
  2. Our study shows that some pathogenic variants in ALG9 can present as a lethal skeletal dysplasia with visceral malformations as the most severe phenotype PMID: 25966638
  3. Due to the ALG9 deficiency, cells accumulated the lipid-linked oligosaccharides Man(6)GlcNAc(2)-PP-dolichol and Man(8)GlcNAc(2)-PP-dolichol. PMID: 19451548
Involvement in disease
Congenital disorder of glycosylation 1L (CDG1L); Gillessen-Kaesbach-Nishimura syndrome (GIKANIS)
Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein Families
Glycosyltransferase 22 family
Tissue Specificity
Ubiquitously expressed; with highest levels in heart, liver and pancreas.
Database Links

HGNC: 15672

OMIM: 263210

KEGG: hsa:79796

STRING: 9606.ENSP00000435517

UniGene: Hs.745155

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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