APOC2 Antibody, HRP conjugated

Datasheet
Code CSB-PA001932OB01HU
Size US$299
Uniprot No. P02655
Immunogen Peptide sequence from Human Apolipoprotein C-II protein (20-38AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. In normolipidemic individuals, it is mainly distributed in the HDL, whereas in hypertriglyceridemic individuals, predominantly found in the VLDL and LDL.
Form Liquid
Conjugate HRP
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Apolipoprotein C-II (Apo-CII) (ApoC-II) (Apolipoprotein C2) [Cleaved into: Proapolipoprotein C-II (ProapoC-II)], APOC2, APC2
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Research Area Cardiovascular
Target Names APOC2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. In normolipidemic individuals, it is mainly distributed in the HDL, whereas in hypertriglyceridemic individuals, predominantly found in the VLDL and LDL.
Involvement in disease Hyperlipoproteinemia 1B (HLPP1B)
Subcellular Location Secreted
Protein Families Apolipoprotein C2 family
Tissue Specificity Liver and intestine.
Database Links

HGNC: 609

OMIM: 207750

KEGG: hsa:344

STRING: 9606.ENSP00000466775

UniGene: Hs.75615

Pathway Cholesterol metabolism

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