ASCC2 Antibody

Datasheet

Code	CSB-PA548485
Size	US$166
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Image	Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: A431 cells, 293T cells, hela cells, Primary antibody: CSB-PA548485(ASCC2 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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Product Details
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Target Background

Product Details

Uniprot No.

Q9H1I8

Target Names

ASCC2

Alternative Names

1700011I11Rik antibody; 2610034L15Rik antibody; Activating signal cointegrator 1 complex subunit 2 antibody; AI482016 antibody; ASC 1 complex subunit p100 antibody; ASC-1 complex subunit p100 antibody; ASC1P100 antibody; ASCC 2 antibody; Ascc2 antibody; ASCC2_HUMAN antibody; AW046480 antibody; FLJ21588 antibody; OTTMUSP00000005258 antibody; p100 antibody; RGD1561422 antibody; RP23-280J3.3 antibody; Trip4 complex subunit p100 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthetic peptide of Human ASCC2

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
WB	1:500-1:2000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. Involved in activation of the ribosome quality control (RQC) pathway, a pathway that degrades nascent peptide chains during problematic translation. As part of the ribosome quality control trigger (RQT) complex, recognizes ZNF598-dependent ubiquitination of stalled ribosomes.

Subcellular Location

Nucleus. Nucleus speckle.

Protein Families

ASCC2 family

Tissue Specificity

Ubiquitous.

Database Links

HGNC: 24103

OMIM: 614216

KEGG: hsa:84164

STRING: 9606.ENSP00000305502

UniGene: Hs.731754

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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