ATL3 Antibody

Datasheet

Code	CSB-PA728503LA01HU
Size	US$166
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Image	Western blot All lanes: ATL3 antibody at 2µg/ml Lane 1: Jurkat whole cell lysate Lane 2: Hela whole cell lysate Lane 3: HepG2 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 61 kDa Observed band size: 61 kDa Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA728503LA01HU at dilution of 1:100 Immunofluorescent analysis of Hela cells using CSB-PA728503LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ATL3 Polyclonal antibody

Uniprot No.

Q6DD88

Target Names

ATL3

Alternative Names

ATL3; Atlastin-3

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Atlastin-3 protein (1-187AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The ATL3 Antibody (Product code: CSB-PA728503LA01HU) is Non-conjugated. For ATL3 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA728503LB01HU	ATL3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA728503LC01HU	ATL3 Antibody, FITC conjugated
Biotin	CSB-PA728503LD01HU	ATL3 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis.

Gene References into Functions

study reports that Sey1/Atl3 and Rtn4 localize to early Legionella-containing vacuoles (LCV) and are critical for pathogen vacuole formation; Sey1/Atl3-dependent ER remodeling contributes to LCV maturation and intracellular replication of L. pneumophila PMID: 28835546
These results suggest that the three ATLs have different capacities to mediate endoplasmic reticulum fusion, with ATL1 being the strongest and ATL3 being the weakest. PMID: 25773277
ATL3 is implicated in the structural organization of intracellular organelles, which may be critical to axonal survival. PMID: 24459106
A family of human GTPases, atlastin-2 and -3 that are closely related to atlastin-1 are described. PMID: 18270207

Involvement in disease

Neuropathy, hereditary sensory, 1F (HSN1F)

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Protein Families

TRAFAC class dynamin-like GTPase superfamily, GB1/RHD3-type GTPase family, GB1 subfamily

Tissue Specificity

Expressed in the central nervous system and in dorsal root ganglia neurons. Expressed in peripheral tissues (at protein level).

Database Links

HGNC: 24526

OMIM: 609369

KEGG: hsa:25923

STRING: 9606.ENSP00000381844

UniGene: Hs.356719

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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