ATP5H Antibody

Code CSB-PA146706
Size US$297
Image
  • Western blot analysis of extracts from HepG2 cells and Jurkat cells, using ATP5H antibody.
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) ATP5H Polyclonal antibody
Uniprot No. O75947
Target Names ATP5H
Alternative Names ATP synthase D chain mitochondrial antibody; ATP synthase H+ transporting mitochondrial F1F0 subunit antibody; ATP synthase H+ transporting mitochondrial F1F0 subunit d antibody; ATP synthase subunit d antibody; ATP synthase subunit d; mitochondrial antibody; ATP synthase; H+ transporting; mitochondrial F0 complex; subunit d antibody; ATP5H antibody; ATP5H_HUMAN antibody; ATP5JD antibody; ATPase subunit d antibody; ATPQ antibody; mitochondrial antibody; My032 protein antibody
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from internal of HumanATP5H.
Immunogen Species Homo sapiens (Human)
Clonality Polyclonal
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration It differs from different batches. Please contact us to confirm it.
Form Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Target Data

Function Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
Gene References into Functions
  1. The Network analyses identified ATP5H expression in temporal cortex in patient with late-onset Alzheimer's disease. PMID: 28242297
  2. By merging results of a meta-GWAS, results in the CHARGE consortium data sets and an in vivo genotyping comprising 4501 individuals, detected a novel locus ATP5H/KCTD2 associated with Alzheimer's disease risk PMID: 23857120
  3. This protein has been found differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia. PMID: 19110265
Subcellular Location Mitochondrion, Mitochondrion inner membrane
Protein Families ATPase d subunit family
Database Links

HGNC: 845

KEGG: hsa:10476

STRING: 9606.ENSP00000301587

UniGene: Hs.514465

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