ATP5H Antibody

Code CSB-PA002366ESR2HU
Size US$166
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Image
  • Western blot
    All lanes: ATP5H antibody at 5.16 μg/ml
    Lane 1: Mouse kidney tissue
    Lane 2: Mouse liver tissue
    Lane 3: Mouse brain tissue
    Lane 4: Hela whole cell lysate
    Lane 5: HepG2 whole cell lysate
    Lane 6: PC-3 whole cell lysate
    Lane 7: U251 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 19, 16 kDa
    Observed band size: 19 kDa

  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA002366ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA002366ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ATP5H Polyclonal antibody
Uniprot No.
Target Names
ATP5H
Alternative Names
ATP synthase D chain mitochondrial antibody; ATP synthase H+ transporting mitochondrial F1F0 subunit antibody; ATP synthase H+ transporting mitochondrial F1F0 subunit d antibody; ATP synthase subunit d antibody; ATP synthase subunit d; mitochondrial antibody; ATP synthase; H+ transporting; mitochondrial F0 complex; subunit d antibody; ATP5H antibody; ATP5H_HUMAN antibody; ATP5JD antibody; ATPase subunit d antibody; ATPQ antibody; mitochondrial antibody; My032 protein antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human ATP synthase subunit d, mitochondrial protein (1-161AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
Gene References into Functions
  1. The Network analyses identified ATP5H expression in temporal cortex in patient with late-onset Alzheimer's disease. PMID: 28242297
  2. By merging results of a meta-GWAS, results in the CHARGE consortium data sets and an in vivo genotyping comprising 4501 individuals, detected a novel locus ATP5H/KCTD2 associated with Alzheimer's disease risk PMID: 23857120
  3. This protein has been found differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia. PMID: 19110265
Subcellular Location
Mitochondrion. Mitochondrion inner membrane.
Protein Families
ATPase d subunit family
Database Links

HGNC: 845

KEGG: hsa:10476

STRING: 9606.ENSP00000301587

UniGene: Hs.514465

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