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| Code | CSB-PA846292LA01HU |
| Size | US$166 |
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The ATP6V0A1 Antibody (Product code: CSB-PA846292LA01HU) is Non-conjugated. For ATP6V0A1 Antibody with conjugates, please check the following table.
| Application | Recommended Dilution |
|---|---|
| WB | 1:500-1:5000 |
| IHC | 1:20-1:200 |
| IF | 1:50-1:200 |
The ATP6V0A1 antibody is designed to recognize the ATP6V0A1 proteins from human, mouse, and rat samples. When a rabbit received an injection of the recombinant human ATP6V0A1 protein (80-260aa), an immune response occurred in the rabbit producing large amounts of antibodies against the ATP6V0A1 protein. The rabbit's blood was collected and isolated to get the anti-serum, which underwent protein G purification to obtain the high-purity ATP6V0A1 polyclonal antibody (purity 95%+). This ATP6V0A1 antibody has accessed its specificity in ELISA, WB, IHC, and IF applications.
The ATP6V0A1 protein, a subunit of the vacuolar ATPase (V-ATPase) enzyme, is specifically involved in the translocation of protons across the membrane and is essential for the proper functioning of the V-ATPase. It is responsible for maintaining the pH balance of the acidic compartments within the cell and plays a critical role in many cellular processes, including protein degradation, membrane trafficking, and ion homeostasis. Mutations in ATP6V0A1 have been linked to several disorders, including renal tubular acidosis and osteopetrosis.
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