Your Good Partner in Biology Research
Your Good Partner in Biology Research
| Code | CSB-PA002398GA01HU |
| Size | US$685 |
| Have Questions? | Leave a Message or Start an on-line Chat |
| Uniprot No. | P21281 |
| Target Names | ATP6V1B2 |
| Alternative Names | ATP6B1B2 antibody; ATP6B2 antibody; ATP6V1 B2 antibody; ATP6V1B 2 antibody; ATP6V1B2 antibody; ATPase H+ transporting lysosomal 56/58kDa V1 subunit B isoform 2 antibody; ATPase H+ transporting lysosomal 56/58kDa V1 subunit B2 antibody; ATPase H+ transporting, lysosomal (vacuolar proton pump) beta polypeptide 56/58kD isoform 2 antibody; ATPase, H+ transporting, lysosomal V1 subunit B2 antibody; brain isoform antibody; Endomembrane proton pump 58 kDa subunit antibody; H+ transporting two sector ATPase antibody; HO 57 antibody; HO57 antibody; V ATPase B2 subunit antibody; V ATPase subunit B 2 antibody; V type proton ATPase subunit B, brain isoform antibody; V-ATPase subunit B 2 antibody; V-type proton ATPase subunit B antibody; Vacuolar ATP synthase subunit B brain isoform antibody; Vacuolar H+ ATPase 56,000 subunit antibody; Vacuolar H+ ATPase 56000 subunit antibody; Vacuolar H+ATPase B2 antibody; Vacuolar proton pump subunit B 2 antibody; VAT B2 antibody; VATB 2 antibody; VATB antibody; VATB2 antibody; VATB2_HUMAN antibody; Vma 2 antibody; Vma2 antibody; VPP 3 antibody; VPP3 antibody |
| Raised in | Rabbit |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Human ATP6V1B2 |
| Immunogen Species | Homo sapiens (Human) |
| Isotype | IgG |
| Purification Method | Antigen Affinity purified |
| Concentration | It differs from different batches. Please contact us to confirm it. |
| Buffer | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Tested Applications | ELISA,WB,IHC |
| Protocols | ELISA Protocol Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol |
| Troubleshooting and FAQs | Antibody FAQs |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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| Function |
Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. In renal intercalated cells, can partially compensate the lack of ATP6V1B1 and mediate secretion of protons (H+) into the urine under base-line conditions but not in conditions of acid load.
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| Gene References into Functions |
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| Involvement in disease | Zimmermann-Laband syndrome 2 (ZLS2); Deafness, congenital, with onychodystrophy, autosomal dominant (DDOD) |
| Subcellular Location | Apical cell membrane. Melanosome. Cytoplasm. |
| Protein Families | ATPase alpha/beta chains family |
| Tissue Specificity | Kidney; localizes to early distal nephron, encompassing thick ascending limbs and distal convoluted tubules (at protein level). |
| Database Links |
HGNC: 854 OMIM: 124480 KEGG: hsa:526 STRING: 9606.ENSP00000276390 UniGene: Hs.295917 |
