Acetyl-ACSS1 (K642) Antibody

Datasheet

Citations (1)

Code	CSB-PA848164
Size	US$119
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Image	Western Blot analysis of 1,293T 2,hela cells using primary antibody diluted at 1:1000(4°C overnight). Secondary antibody:Goat Anti-rabbit IgG IRDye 800( diluted at 1:5000, 25°C, 1 hour)
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Product Details
Citations
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9NUB1

Target Names

ACSS1

Alternative Names

ACAS2L antibody; AceCS2 antibody; AceCS2L antibody; Acetate CoA ligase 2 antibody; Acetate--CoA ligase 2 antibody; Acetyl CoA synthetase 2 antibody; Acetyl Coenzyme A synthetase 2 (AMP forming) like antibody; Acetyl coenzyme A synthetase 2 like; mitochondrial antibody; Acetyl-CoA synthetase 2 antibody; Acetyl-coenzyme A synthetase 2-like; mitochondrial antibody; ACS2L_HUMAN antibody; Acss1 antibody; Acyl CoA synthetase short chain family member 1 antibody; Acyl-CoA synthetase short-chain family member 1 antibody; FLJ45659 antibody; KIAA1846 antibody; MGC33843 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthesized Acetyl peptide derived from Human ACSS1. at AA range: K642

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB,ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-2000
ELISA	1:10000-20000

Protocols

Western Blotting(WB) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Citations

SPC-180002, a SIRT1/3 dual inhibitor, impairs mitochondrial function and redox homeostasis and represents an antitumor activity Y Cho,Free radical biology & medicine,2023

Customer Reviews and Q&A

■ Customer Reviews

Average Rating:

5.0 - 1 reviews

Submit a Review here

Applications : WB

Sample type: Cells

Review: acyl-CoA synthetase short chain family member 1 (ACSS1).

By Anonymous

Target Background

Function

Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also utilize propionate with a much lower affinity. Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions. Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient.

Gene References into Functions

citrate synthase and ACSS1 have tumorigenic functions in hepatocellular carcinoma PMID: 27363021
ACSS1 is essential for glucose-independent acetate-mediated cell survival and tumor growth. PMID: 27539851

Subcellular Location

Mitochondrion matrix.

Protein Families

ATP-dependent AMP-binding enzyme family

Database Links

HGNC: 16091

OMIM: 614355

KEGG: hsa:84532

STRING: 9606.ENSP00000316924

UniGene: Hs.529353

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Phage Display Service

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Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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