ACSS1 Antibody

Code CSB-PA882105ZA01HU
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ACSS1 Polyclonal antibody
Uniprot No.
Target Names
ACSS1
Alternative Names
ACAS2L antibody; AceCS2 antibody; AceCS2L antibody; Acetate CoA ligase 2 antibody; Acetate--CoA ligase 2 antibody; Acetyl CoA synthetase 2 antibody; Acetyl Coenzyme A synthetase 2 (AMP forming) like antibody; Acetyl coenzyme A synthetase 2 like; mitochondrial antibody; Acetyl-CoA synthetase 2 antibody; Acetyl-coenzyme A synthetase 2-like; mitochondrial antibody; ACS2L_HUMAN antibody; Acss1 antibody; Acyl CoA synthetase short chain family member 1 antibody; Acyl-CoA synthetase short-chain family member 1 antibody; FLJ45659 antibody; KIAA1846 antibody; MGC33843 antibody
Raised in
Rabbit
Species Reactivity
Homo sapiens
Immunogen
Recombinant Homo sapiens ACSS1 protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Protein A/G
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also utilize propionate with a much lower affinity. Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions. Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient.
Gene References into Functions
  1. citrate synthase and ACSS1 have tumorigenic functions in hepatocellular carcinoma PMID: 27363021
  2. ACSS1 is essential for glucose-independent acetate-mediated cell survival and tumor growth. PMID: 27539851
Subcellular Location
Mitochondrion matrix.
Protein Families
ATP-dependent AMP-binding enzyme family
Database Links

HGNC: 16091

OMIM: 614355

KEGG: hsa:84532

STRING: 9606.ENSP00000316924

UniGene: Hs.529353

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 322 (CUBIO Innovation Center), Houston, TX 77054, USA
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