BCAT2 Antibody

Code CSB-PA002601GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
BCAT2
Alternative Names
BCAM antibody; BCAT 2 antibody; BCAT(m) antibody; BCAT2 antibody; BCAT2_HUMAN antibody; BCATM antibody; BCT2 antibody; Branched chain aminotransferase 2; mitochondrial antibody; Branched-chain-amino-acid aminotransferase antibody; ECA40 antibody; mitochondrial antibody; Placental protein 18 antibody; PP18 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Human BCAT2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20℃, Avoid freeze / thaw cycles.
Form
Liquid
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids.
Gene References into Functions
  1. identification of a peroxide-sensitive redox switch at the CXXC motif PMID: 12119021
  2. Studies of ketimine and pyridoxamine phosphate forms of BCAT@ reaction intermediates reveal substrate specificity for L-branched chain amino acids via a group of hydrophobic residues that form three hydrophobic surfaces and lock the side chain in place. PMID: 12269802
  3. role of cysteine residues in the regulatory CXXC motif PMID: 15182179
  4. ption of the CXXC center results in altered substrate orientation and deprotonation of the amino group of pyridoxamine 5'-phosphate, which inhibits catalysis PMID: 17050531
Subcellular Location
[Isoform A]: Mitochondrion.; [Isoform B]: Cytoplasm.
Protein Families
Class-IV pyridoxal-phosphate-dependent aminotransferase family
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 977

OMIM: 113530

KEGG: hsa:587

STRING: 9606.ENSP00000322991

UniGene: Hs.512670

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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