BMP8B Antibody

Code CSB-PA001031
Size US$100
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  • Western Blot analysis of A549 cells using BMP-8B Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
BMP8B
Alternative Names
BMP-8 antibody; BMP-8B antibody; BMP8 antibody; Bmp8b antibody; BMP8B_HUMAN antibody; bone morphogenetic protein 8 (osteogenic protein 2) antibody; Bone morphogenetic protein 8 antibody; Bone morphogenetic protein 8B antibody; dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)) antibody; OP-2 antibody; OP2 antibody; Osteogenic protein 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human BMP-8B.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
Gene References into Functions
  1. Acetylated H3K9 and H4K16 levels at BMP8B were increased in gastric cancer (GC) compared to nontumors (P < 0.05). However, reduced levels of acetylated H3K9 and H4K16 were associated with poorly differentiated GC (P < 0.05). PMID: 27748538
  2. Study found that BMP8B was downregulated in pancreatic cancer tissues and BMP8B mediates the survival of pancreatic cancer cells and regulates the progression of pancreatic cancer. PMID: 25176058
  3. Five novel SNPs within BMP8B gene.Genetic variants in BMP8B gene are associated with growth traits in Chinese native cattle. PMID: 24076131
  4. Epigenetic silencing of the bone morphogenetic protein 2 gene through methylation is associated with gastric carcinomas PMID: 16314833
  5. Reports on the mouse homolog of this gene. PMID: 9070944

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Subcellular Location
Secreted.
Protein Families
TGF-beta family
Database Links

HGNC: 1075

OMIM: 602284

KEGG: hsa:656

STRING: 9606.ENSP00000361915

UniGene: Hs.734367

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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