CCNL1 Antibody

1. Results suggest that LEKR1-CCNL1 and IGSF21-KLHDC7A gene polymorphisms influence the development of diabetic retinopathy (DR). PMID: 27607899
2. CCNL1 is the target gene of miR-199b-5p. PMID: 26043836
3. Data indicate that if the newborn carried a risk allele rs900400 near LEKR/CCNL1, the impact of stress on birth size was stronger. PMID: 22685556
4. birth weight lowering effect of the C-allele of rs900400 located near LEKR1 and CCNL1 was replicated in the Danish population. Furthermore the C-allele was associated with increased insulin response following oral glucose stimulation PMID: 22073261
5. Data show low birth weight in Asian Indians is not due to variation near CCNL1/ADCY5, but variant ADCY5 is associated with elevated glucose/decreased insulin response which suggests a common genetic cause of low birth weight and risk of type 2 diabetes. PMID: 21712988
6. These data demonstrate that there is a fine balance between CCNL1 and TIMP1, which may contribute to breast cancer development. PMID: 21586274
7. Our results suggest that a genetic variant of ccnl1 leads to symmetric growth restriction from early pregnancy onward PMID: 21307140
8. Cyclin L1 amplification is associated with uterine cervical carcinoma. PMID: 20721974
9. variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight PMID: 20372150
10. role in pre-mRNA splicing PMID: 11980906
11. Our results indicate that CCNL1 plays a critical role in the loco-regional progression of HNSCC and may serve as an indicator for occult advanced tumour stages. PMID: 15700036
12. study suggests that cyclin l1 may have a role in RNA processing complex anc ould participate in tumor progression of head and neck squamous cell carcinoma PMID: 16598186
13. Data show that a green fluorescent protein (GFP) fusion protein of cyclin L1, in contrast to cyclin L2, was not mobile within the nucleus of living COS7 cells. PMID: 17494991
14. CDK11(p110) interacts physically and functionally with cyclin Lalpha and -beta isoforms and SR proteins to regulate splicing. PMID: 18216018
15. Cyclin L has been shown to associate with the PITSLRE kinase and is involved in pre-mRNA processing. PMID: 11980906

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HGNC: 20569

OMIM: 613384

KEGG: hsa:57018

STRING: 9606.ENSP00000295926

UniGene: Hs.4859