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| Code | CSB-PA004840LA01HU |
| Size | US$299 |
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| Description |
The recombinant human C-C chemokine receptor type 10 (CCR10) protein (314-362AA) is used to immunize rabbits to obtain the CCR10 antibody. This CCR10 polyclonal antibody exists as an unconjugated IgG. It has undergone protein G purification and reaches up to 95% in purity. It only shows reactivity with human CCR10 protein. Quality tests of this antibody have been validated in ELISA, WB, IHC, and IF assays. The target protein CCR10 is the receptor for CCL27 and CCL28. CCR10 interacting with CCL27 is involved in T cell-mediated skin inflammation. CCR10/CCL28 interactions are essential for efficient accumulation of antigen-specific IgA plasma cells to the murine large intestine and mammary gland. |
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| Full Product Name | Rabbit anti-Homo sapiens (Human) CCR10 Polyclonal antibody | ||||||||
| Uniprot No. | P46092 | ||||||||
| Target Names | CCR10 | ||||||||
| Alternative Names |
CCR10; GPR2; C-C chemokine receptor type 10; C-C CKR-10; CC-CKR-10; CCR-10; G-protein coupled receptor 2
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| Raised in | Rabbit | ||||||||
| Species Reactivity | Human | ||||||||
| Immunogen | Recombinant Human C-C chemokine receptor type 10 protein (314-362AA) | ||||||||
| Immunogen Species | Homo sapiens (Human) | ||||||||
| Conjugate | Non-conjugated The CCR10 Antibody (Product code: CSB-PA004840LA01HU) is Non-conjugated. For CCR10 Antibody with conjugates, please check the following table. |
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| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Purification Method | >95%, Protein G purified | ||||||||
| Concentration | It differs from different batches. Please contact us to confirm it. | ||||||||
| Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
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| Form | Liquid | ||||||||
| Tested Applications | ELISA, WB, IHC, IF | ||||||||
| Recommended Dilution |
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| Protocols | ELISA Protocol Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol Immunofluorescence (IF) Protocol |
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| Troubleshooting and FAQs | Antibody FAQs | ||||||||
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||||||
| Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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| Function |
Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line.
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| Gene References into Functions |
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| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Protein Families | G-protein coupled receptor 1 family |
| Tissue Specificity | Expressed at high levels in adult testis, small intestine, fetal lung, fetal kidney. Weaker expression was observed in many other adult tissues including spleen, thymus, lymph node, Peyer patches, colon, heart, ovary, peripheral blood lymphocytes, thyroid |
| Database Links |
HGNC: 4474 OMIM: 600240 KEGG: hsa:2826 STRING: 9606.ENSP00000332504 UniGene: Hs.744542 |
