CD300C Antibody

Datasheet

Code	CSB-PA006279
Size	US$119
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Image	Western Blot analysis of RAT-kidney cells using CD300c Polyclonal Antibody Western Blot analysis of rat kidney cells using CD300c Polyclonal Antibody
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q08708

Target Names

CD300C

Alternative Names

CD300 antigen-like family member C antibody; CD300c antibody; CD300c antigen antibody; CD300c molecule antibody; CLM-6 antibody; CLM6_HUMAN antibody; CMRF-35 antibody; CMRF-35A antibody; CMRF35 antibody; CMRF35 antigen antibody; CMRF35 leukocyte immunoglobulin-like receptor antibody; CMRF35-A1 antibody; CMRF35-like molecule 6 antibody; CMRF35A antibody; CMRF35A leukocyte immunoglobulin-like receptor antibody; CMRF35A1 antibody; IgSF16 antibody; Immunoglobulin superfamily member 16 antibody; LIR antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of Human CD300c.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:10000

Protocols

Western Blotting(WB) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Gene References into Functions

Results show that CD300c is exclusively expressed on CD56bright natural killer cells and differentially binds to phosphatidylethanolamine and phosphatidylserine. This expression is under the regulation of STAT5 and Il-4. PMID: 27040328
potential role in inflammatory responses PMID: 23571507
engagement of CD300C led to Fc receptor gamma-dependent activation of mast cells and monocytes PMID: 23372157
differential expression on human TH1 and TH17 cell memory subsets PMID: 22046970
CD300a and CD300c receptors are indistinguishable on the surface of natural killer (NK) cells. The tyrosine residue in the third ITIM motif, Tyr-267-Ala, is the most important residue for execution of the inhibitory signal. PMID: 20656921
CMRF35A and CMRF35H have roles in immunoglobulin signaling; CMRF35A induces cellular activation and effector function [review] PMID: 12456026
CD300a and CD300c play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs; CD300a/c RNA and surface expression were downregulated after stimulation of pDCs with TLR7 and TLR9 ligands PMID: 18535206

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Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Protein Families

CD300 family

Tissue Specificity

Present on the surface of monocytes, neutrophils, a proportion of peripheral blood T- and B-lymphocytes and lymphocytic cell lines.

Database Links

HGNC: 19320

OMIM: 606786

KEGG: hsa:10871

STRING: 9606.ENSP00000329507

UniGene: Hs.2605

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Target Therapy

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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