CDC42EP2 Antibody

Datasheet

Code	CSB-PA005013LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA005013LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA005013LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CDC42EP2 Polyclonal antibody

Uniprot No.

O14613

Target Names

CDC42EP2

Alternative Names

Binder of Rho GTPases 1 antibody; BORG1 antibody; BORG1_HUMAN antibody; CDC42 effector protein (Rho GTPase binding) 2 antibody; Cdc42 effector protein 2 antibody; Cdc42ep2 antibody; CEP2 antibody; CRIB-containing BOGR1 protein antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Cdc42 effector protein 2 protein (9-210AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The CDC42EP2 Antibody (Product code: CSB-PA005013LA01HU) is Non-conjugated. For CDC42EP2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA005013LB01HU	CDC42EP2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA005013LC01HU	CDC42EP2 Antibody, FITC conjugated
Biotin	CSB-PA005013LD01HU	CDC42EP2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.

Gene References into Functions

Studies indicate some of the functional and mechanistic roles of the binder of Rho GTPases Borg1-5 proteins (Cdc42EP1-5), including cytoskeletal remodelling and signalling. PMID: 27913681
CDC42EP2 is upregulated in human PDLCs subjected to tensile stress related to mechano-induced cell cycle arrest. PMID: 20934684
activations of Rac1 and Cdc42 are involved in the hypoxia-induced production of angiogenesis-promoting factors and tumor suppressors, and suggest that the Rho family GTPases Rac1 and Cdc42 may contribute to the hypoxia-mediated angiogenesis. PMID: 16395716

Subcellular Location

Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.

Protein Families

BORG/CEP family

Tissue Specificity

Highly expressed in the heart. Weakly expressed in the pancreas and liver.

Database Links

HGNC: 16263

OMIM: 606132

KEGG: hsa:10435

STRING: 9606.ENSP00000279249

UniGene: Hs.343380

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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