CDCA4 Antibody

Datasheet

Code	CSB-PA597809
Size	US$297
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Image	Immunohistochemistry analysis of paraffin-embedded human brain tissue using CDCA4 antibody. Immunofluorescence analysis of HepG2 cells, using CDCA4 antibody.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CDCA4 Polyclonal antibody

Uniprot No.

Q9BXL8

Target Names

CDCA4

Alternative Names

CDCA 4 antibody; Cdca4 antibody; CDCA4_HUMAN antibody; Cell division cycle associated 4 antibody; Cell division cycle-associated protein 4 antibody; FLJ20764 antibody; FLJ52878 antibody; Hematopoietic progenitor protein antibody; Hepp antibody; MGC19517 antibody; SEI 3 antibody; SEI-3/HEPP antibody; SEI3 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthesized peptide derived from internal of Human CDCA4.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,IHC,IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:50-1:100
IF	1:100-1:500

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

May participate in the regulation of cell proliferation through the E2F/RB pathway. May be involved in molecular regulation of hematopoietic stem cells and progenitor cell lineage commitment and differentiation.

Gene References into Functions

The results confirmed that CDCA4 RNA interference reduced the percentage of human breast cancer cells to <50%. In addition, RNA interference of CDCA4 resulted in a significant increase in the apoptotic rate of cells. PMID: 29257222
High CDCA4 expression is associated with malignant melanoma. PMID: 27492455
CDCA4 participates in the regulation of cell proliferation, mainly through the E2F/retinoblastoma protein pathway PMID: 16984923
Data suggest that CDCA4 is involved in spindle organization from prometaphase, and when anaphase begins, it may play a different role as a midzone factor involved in chromosome segregation or cytokinesis. PMID: 18498124
an important role of CDCA4 in the context of transcriptional regulation and cell fate determination through the JUN oncogene PMID: 18572021
Isolation of the mouse ortholog and comparison to the human protein. PMID: 11482882

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Subcellular Location

Nucleus.

Tissue Specificity

Highest levels of expression in the pancreas, thymus, testis, spleen, liver, placenta and leukocytes. Relatively low levels in the lung, kidney, prostate, ovary, small intestine and colon. Hardly detectable, if at all, in the brain, skeletal muscle and he

Database Links

HGNC: 14625

OMIM: 612270

KEGG: hsa:55038

STRING: 9606.ENSP00000337226

UniGene: Hs.34045

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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