CEP97 Antibody

Datasheet
Code CSB-PA186887
Size US$299
Uniprot No. Q8IW35
Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA186887(CEP97 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA186887(CEP97 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
  • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-5: 293T cells, hela cells, PC3 cells, lovo cells, A172 cells, Primary antibody: CSB-PA186887(CEP97 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Fusion protein of Human CEP97
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA,WB,IHC;ELISA:1:2000-1:5000,WB:1:500-1:2000,IHC:1:25-1:100
Relevance Centrosomal protein of 97 kDa (Cep97), also known as leucine-rich repeat and IQ domain-containing protein 2 (LRRIQ2), is a protein that in humans is encoded by the CEP97 gene. Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome. Interacts with CALM1, CEP76 and CCP110. Via its interaction with CCP110, may indirectly interact with HERC2 and NEURL4. Interacts with KIF24.
Form Liquid
Conjugate Non-conjugated
Storage Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method Antigen affinity purification
Isotype IgG
Alias centrosomal protein 97kDa
Immunogen Species Homo sapiens (Human)
Target Names CEP97
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Database Links

HGNC: 26244

OMIM: 615864

KEGG: hsa:79598

STRING: 9606.ENSP00000342510

UniGene: Hs.444135

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