CHRND Antibody, Biotin conjugated

Datasheet
Code CSB-PA005399LD01HU
Size US$299
Uniprot No. Q07001
Protocols ELISA Protocol
Immunogen Recombinant Human Acetylcholine receptor subunit delta protein (334-471AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Acetylcholine receptor subunit delta, CHRND, ACHRD
Immunogen Species Homo sapiens (Human)
Research Area Neuroscience
Target Names CHRND
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Involvement in disease Multiple pterygium syndrome, lethal type (LMPS); Myasthenic syndrome, congenital, 3A, slow-channel (CMS3A); Myasthenic syndrome, congenital, 3B, fast-channel (CMS3B); Myasthenic syndrome, congenital, 3C, associated with acetylcholine receptor deficiency (CMS3C)
Subcellular Location Cell junction, synapse, postsynaptic cell membrane, Multi-pass membrane protein, Cell membrane, Multi-pass membrane protein
Protein Families Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) subfamily, Delta/CHRND sub-subfamily
Database Links

HGNC: 1965

OMIM: 100720

KEGG: hsa:1144

STRING: 9606.ENSP00000258385

UniGene: Hs.156289

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