CLGN Antibody

Code CSB-PA005544LA01HU
Size US$166
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  • Western blot
    All lanes: CLGN antibody at 7µg/ml
    Lane 1: Mouse brain tissue
    Lane 2: Mouse lung tissue
    Lane 3: Jurkat whole cell lysate
    Lane 4: HepG2 whole cell lysate
    Lane 5: PC-3 whole cell lysate
    Lane 6: Hela whole cell lysate
    Lane 7: HL60 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 71, 47 kDa
    Observed band size: 80 kDa

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA005544LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA005544LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CLGN Polyclonal antibody
Uniprot No.
Target Names
CLGN
Alternative Names
CLGN; Calmegin
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Calmegin protein (200-400AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CLGN Antibody (Product code: CSB-PA005544LA01HU) is Non-conjugated. For CLGN Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA005544LB01HU CLGN Antibody, HRP conjugated ELISA
FITC CSB-PA005544LC01HU CLGN Antibody, FITC conjugated
Biotin CSB-PA005544LD01HU CLGN Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. Required for normal sperm migration from the uterus into the oviduct. Required for normal male fertility. Binds calcium ions.
Gene References into Functions
  1. In gene-based analysis CLGN1 represented one of a cluster of genes, which interacted with sodium to influence Blood Pressure. PMID: 27271309
  2. Although their similarity in carbohydrate binding specificities is high, there seems to be some differences in the mode of substrate recognition between calmegin and calnexin. PMID: 24769397
  3. calmegin expression is regulated by histone deacetylase and CpG methyltransferase in a coordinative way PMID: 16264275
Subcellular Location
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein Families
Calreticulin family
Tissue Specificity
Detected in testis (at protein level). Detected in testis.
Database Links

HGNC: 2060

OMIM: 601858

KEGG: hsa:1047

STRING: 9606.ENSP00000326699

UniGene: Hs.86368

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