CLGN Antibody

Code CSB-PA005544LA01HU
Size US$299 How to order?
Image
  • Western blot
    All lanes: CLGN antibody at 7µg/ml
    Lane 1: Mouse brain tissue
    Lane 2: Mouse lung tissue
    Lane 3: Jurkat whole cell lysate
    Lane 4: HepG2 whole cell lysate
    Lane 5: PC-3 whole cell lysate
    Lane 6: Hela whole cell lysate
    Lane 7: HL60 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 71, 47 kDa
    Observed band size: 80 kDa

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA005544LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA005544LA01HU at dilution of 1:100

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) CLGN Polyclonal antibody
Uniprot No. O14967
Target Names CLGN
Alternative Names CLGN; Calmegin
Raised in Rabbit
Species Reactivity Human, Mouse
Immunogen Recombinant Human Calmegin protein (200-400AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated

The CLGN Antibody (Product code: CSB-PA005544LA01HU) is Non-conjugated. For CLGN Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA005544LB01HU CLGN Antibody, HRP conjugated ELISA
FITC CSB-PA005544LC01HU CLGN Antibody, FITC conjugated
Biotin CSB-PA005544LD01HU CLGN Antibody, Biotin conjugated ELISA
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. Required for normal sperm migration from the uterus into the oviduct. Required for normal male fertility. Binds calcium ions.
Gene References into Functions
  1. In gene-based analysis CLGN1 represented one of a cluster of genes, which interacted with sodium to influence Blood Pressure. PMID: 27271309
  2. Although their similarity in carbohydrate binding specificities is high, there seems to be some differences in the mode of substrate recognition between calmegin and calnexin. PMID: 24769397
  3. calmegin expression is regulated by histone deacetylase and CpG methyltransferase in a coordinative way PMID: 16264275
Subcellular Location Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein Families Calreticulin family
Tissue Specificity Detected in testis (at protein level). Detected in testis.
Database Links

HGNC: 2060

OMIM: 601858

KEGG: hsa:1047

STRING: 9606.ENSP00000326699

UniGene: Hs.86368

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