COA1 Antibody

Code CSB-PA004170LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA004170LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA004170LA01HU at dilution of 1:100

  • Immunofluorescent analysis of U251 cells using CSB-PA004170LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) COA1 Polyclonal antibody
Uniprot No.
Target Names
COA1
Alternative Names
COA1 antibody; C7orf44 antibody; MITRAC15Cytochrome c oxidase assembly factor 1 homolog antibody; Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 15 kDa antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Cytochrome c oxidase assembly factor 1 homolog protein (38-146AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The COA1 Antibody (Product code: CSB-PA004170LA01HU) is Non-conjugated. For COA1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA004170LB01HU COA1 Antibody, HRP conjugated ELISA
FITC CSB-PA004170LC01HU COA1 Antibody, FITC conjugated
Biotin CSB-PA004170LD01HU COA1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for assembly of mitochondrial respiratory chain complex I and complex IV.
Gene References into Functions
  1. Restoration of miR-127-3p and miR-376a-3p counteracts the neoplastic phenotype of giant cell tumor of bone derived stromal cells by targeting COA1, GLE1 and PDIA6. PMID: 26655997
  2. Human ortholog of fungal COA1 (Cytochrome Oxidase Assembly 1) PMID: 22356826
Subcellular Location
Mitochondrion inner membrane; Single-pass membrane protein.
Protein Families
COA1 family
Database Links

HGNC: 21868

OMIM: 614769

KEGG: hsa:55744

UniGene: Hs.268887

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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