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CD47｜Proteinase K｜EGFR｜BCMA｜PD-L1｜CD276｜ACE2｜TMPRSS2｜Exosome Isolation Kits
Your Good Partner in Biology Research
CD47｜Proteinase K｜EGFR｜BCMA｜PD-L1｜CD276｜ACE2｜TMPRSS2｜Exosome Isolation Kits
| Code | CSB-PA005789ESR1HU |
| Size |
US$167Purchase it in Cusabio online store (only available for customers from the US) |
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| Full Product Name | Rabbit anti-Homo sapiens (Human) COPS2 Polyclonal antibody | ||||||
| Uniprot No. | P61201 | ||||||
| Target Names | COPS2 | ||||||
| Alternative Names | ALIEN antibody; Alien Drosophila himolog of antibody; Alien homolog antibody; COP 9 antibody; COP9 antibody; COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) antibody; COP9 constitutive photomorphogenic homolog subunit 2 antibody; COP9 signalosome complex subunit 2 antibody; COPS 2 antibody; Cops2 antibody; CSN2 antibody; CSN2_HUMAN antibody; JAB1 containing signalosome subunit 2 antibody; JAB1-containing signalosome subunit 2 antibody; SGN 2 antibody; SGN2 antibody; Signalosome subunit 2 antibody; Thyroid Hormone Receptor Interactor15 antibody; Thyroid Hormone Receptor Interactor 15 antibody; Thyroid receptor-interacting protein 15 antibody; TR-interacting protein 15 antibody; TRIP 15 antibody; TRIP-15 antibody; TRIP15 antibody | ||||||
| Raised in | Rabbit | ||||||
| Species Reactivity | Human, Mouse | ||||||
| Immunogen | Recombinant Human COP9 signalosome complex subunit 2 protein (1-310AA) | ||||||
| Immunogen Species | Homo sapiens (Human) | ||||||
| Conjugate | Non-conjugated | ||||||
| Clonality | Polyclonal | ||||||
| Isotype | IgG | ||||||
| Purification Method | Antigen Affinity Purified | ||||||
| Concentration | It differs from different batches. Please contact us to confirm it. | ||||||
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | ||||||
| Form | Liquid | ||||||
| Tested Applications | ELISA, WB, IHC | ||||||
| Recommended Dilution |
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| Protocols | ELISA Protocol Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol |
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| Troubleshooting and FAQs | Antibody FAQs | ||||||
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||||
| Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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| Function | Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1. |
| Gene References into Functions |
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| Subcellular Location | Cytoplasm, Nucleus |
| Protein Families | CSN2 family |
| Database Links |
HGNC: 30747 OMIM: 604508 KEGG: hsa:9318 STRING: 9606.ENSP00000299259 UniGene: Hs.369614 |
