CPNE3 Antibody

Code CSB-PA005902GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
CPNE3
Alternative Names
Copine 3 antibody; Copine III antibody; Copine-3 antibody; Copine3 antibody; CopineIII antibody; CPN3 antibody; CPNE 3 antibody; CPNE3 antibody; CPNE3_HUMAN antibody; KIAA0636 antibody; PRO1071 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human CPNE3
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Calcium-dependent phospholipid-binding protein that plays a role in ERBB2-mediated tumor cell migration in response to growth factor heregulin stimulation.
Gene References into Functions
  1. CPNE3(high) is an adverse prognostic biomarker for acute myeloid leukemia. PMID: 28670859
  2. Copine3 binding to ErbB2 increases when Jab1 is overexpressed in SKBr3 breast cancer cells. Copine3 and Jab1 binding regulates the ErbB2 signaling pathway. PMID: 26719032
  3. our results indicate that CPNE3 could play a critical role in NSCLC metastasis. PMID: 23713811
  4. This study demonistrated that dysregulation of cpne3 3'UTR in brain of patient with schizophrenia. PMID: 23062752
  5. Data suggest that Copine-III is a novel player in the regulation of ErbB2-dependent cancer cell motility. PMID: 20010870
  6. Susceptibility genes CPNE3, IL16 and CDH13 with moderate effects associated with susceptibility to prostate cancer. PMID: 18264096

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Subcellular Location
Nucleus. Cytoplasm. Cell membrane. Cell junction. Cell junction, focal adhesion.
Protein Families
Copine family
Tissue Specificity
Expressed in breast and weakly in prostate and ovarian tissues. Expressed in neutrophils (at protein level). Widely expressed. Expressed in the brain. Expressed in neutrophil precursors from the bone marrow and peripheral blood. Expressed in primary breas
Database Links

HGNC: 2316

OMIM: 604207

KEGG: hsa:8895

STRING: 9606.ENSP00000198765

UniGene: Hs.191219

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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