Code | CSB-PA842761ESR1HU |
Size | US$166 |
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Application | Recommended Dilution |
---|---|
WB | 1:1000-1:5000 |
IHC | 1:20-1:200 |
CRBN polyclonal antibody CSB-PA842761ESR1HU was produced in the rabbit immunized with the recombinant human cereblon protein (1-280aa). The target protein CRBN is a substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates target proteins' ubiquitination and subsequent proteasomal degradation. It is involved in DNA damage repair, cell proliferation, and differentiation.
This rabbit anti-human CRBN polyclonal antibody was tested in the ELISA, WB, and IHC applications. The non-conjugated IgG got purified by antigen affinity chromatography. It reacts with the CRBN proteins of human or mouse origin and may be used to detect the endogenous levels of CRBN protein.
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