CSNK1E Antibody

Code CSB-PA006068GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
CSNK1E
Alternative Names
Casein kinase 1 epsilon antibody; Casein kinase I antibody; Casein kinase I epsilon antibody; Casein kinase I isoform epsilon antibody; CKI epsilon antibody; CKI-epsilon antibody; CKIe antibody; CKIepsilon antibody; CSNK 1E antibody; CSNK1E antibody; DBT antibody; Doubletime, Drosophila, homolog of antibody; EC 2.7.11.1 antibody; epsilon isoform antibody; HCK IE antibody; KC1E antibody; KC1E_HUMAN antibody; kinase CK1 epsilon antibody; MGC 10398 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human CSNK1E
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1 and DVL2. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation.
Gene References into Functions
  1. CKI-epsilon is a potent TDP-43 kinase in vivo and in vitro. PMID: 24105464
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily
Tissue Specificity
Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. Expressed in monocytes and lymphocytes but not in granulocytes.
Database Links

HGNC: 2453

OMIM: 600863

KEGG: hsa:102800317

STRING: 9606.ENSP00000352929

UniGene: Hs.474833

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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