CSNK1E Antibody

Code CSB-PA01315A0Rb
Size US$166
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Image
  • Western Blot
    Positive WB detected in: SH-SY5Y whole cell lysate
    All lanes: CSNK1E antibody at 3µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 48 kDa
    Observed band size: 48 kDa

  • IHC image of CSB-PA01315A0Rb diluted at 1:150 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

  • IHC image of CSB-PA01315A0Rb diluted at 1:150 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CSNK1E Polyclonal antibody
Uniprot No.
Target Names
CSNK1E
Alternative Names
Casein kinase 1 epsilon antibody; Casein kinase I antibody; Casein kinase I epsilon antibody; Casein kinase I isoform epsilon antibody; CKI epsilon antibody; CKI-epsilon antibody; CKIe antibody; CKIepsilon antibody; CSNK 1E antibody; CSNK1E antibody; DBT antibody; Doubletime, Drosophila, homolog of antibody; EC 2.7.11.1 antibody; epsilon isoform antibody; HCK IE antibody; KC1E antibody; KC1E_HUMAN antibody; kinase CK1 epsilon antibody; MGC 10398 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Casein kinase I isoform epsilon protein (17-231AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CSNK1E Antibody (Product code: CSB-PA01315A0Rb) is Non-conjugated. For CSNK1E Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA01315B0Rb CSNK1E Antibody, HRP conjugated ELISA
FITC CSB-PA01315C0Rb CSNK1E Antibody, FITC conjugated
Biotin CSB-PA01315D0Rb CSNK1E Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1 and DVL2. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation.
Gene References into Functions
  1. CKI-epsilon is a potent TDP-43 kinase in vivo and in vitro. PMID: 24105464
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily
Tissue Specificity
Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. Expressed in monocytes and lymphocytes but not in granulocytes.
Database Links

HGNC: 2453

OMIM: 600863

KEGG: hsa:102800317

STRING: 9606.ENSP00000352929

UniGene: Hs.474833

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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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