CST7 Antibody

1. during monocyte to macrophage differentiation, the endosomal/lysosomal proteolytic activity can be regulated by cystatin F whose expression is under the control of transcriptional factor C/EBP alpha. PMID: 30033148
2. Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells. PMID: 22365146
3. Transgenic cystatin F is expressed in model mice only during demyelination; in chronic demyelination, remyelinating ability is lost. PMID: 21344476
4. cystatin F is an intracellular cysteine peptidase inhibitor with readily regulated expression PMID: 12423348
5. CST7 is secreted, but artificial modification of its C-terminus can induce its endocytic targeting. PMID: 15212960
6. Cystatin F was not colocalized with cystatin C shich suggests distinct functions for these two cysteine protease inhibitors in U937 cells. PMID: 15752368
7. analysis of reduction-dependent activation of human cystatin F PMID: 16601115
8. A latent protease inhibitor which is itself regulated by proteolysis in the endocytic pathway. PMID: 18256700
9. Data demonstrate the addition of N-linked sugars to an Asn-X-Cys motif in cystatin F and suggest that the mannose 6-phosphate sorting machinery is used to divert cystatin F from the secretory pathway and to mediate its uptake from extracellular pools. PMID: 19192250

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HGNC: 2479

OMIM: 603253

KEGG: hsa:8530

STRING: 9606.ENSP00000420384

UniGene: Hs.143212