CTNNBL1 Antibody

1. CTNNBL1 regulates multiple splicing events and gene expression in ovarian cancer cells PMID: 28501461
2. Tthis study identified WNT5B and CTNNBL1 for peak bone mineral density and body composition in males from the Han Chinese ethnic group. PMID: 26733379
3. The results show that CTNNBL1 enhances the association of CWC15 and CDC5L, both core Prp19 complex proteins and identify an overlap in the region of CDC5L that binds either CTNNBL1 or CWC15 suggesting the two proteins might exchange places in the complex. PMID: 26130721
4. Variants in the gene CTNNBL1 (encoding catenin-beta-like 1, located on chromosome 20 q11.23-q12) have been found to be associated with verbal episodic memory performance. PMID: 25268258
5. The crystal structure of CTNNBL1 shows that the protein coalphansists mainly of alpha-helices and forms an armadillo (ARM) repeat. structure PMID: 24598747
6. Results indicate CTNNBL1 as a unique selective nuclear localization signals (NLSs)-binding protein with striking differences from karyopherin-alphas. PMID: 24269683
7. CTNNBL1 crystal structure provides critical insights into the molecular interactions between CTNNBL1 and its protein partners. PMID: 23897482
8. From this gene expression data and fMRI experiments suggests a role for the beta-catenin-like protein 1 in human episodic memory. PMID: 22105620
9. There are abnormal expression of beta-catenin and activation of Wnt signaling pathway in human esophageal carcinoma cell line Eca-109. PMID: 21215100
10. There was a significantly positive correlation between LMP1 expression and abnormal expression of beta-catenin in nasopharyngeal carcinoma tissue. PMID: 21055033
11. CTNNBL1 is a novel nuclear localization sequence-binding protein that recognizes RNA-splicing factors CDC5L and Prp31 PMID: 21385873
12. Study suggests a novel mechanism for the development of obesity, where CTNNBL1 may play an important role. PMID: 18325910
13. The results, therefore, identify residues in AID involved in its in vivo targeting and suggest they might act through interaction with CTNNBL1, giving possible insight into the linkage between AID recruitment and target-gene transcription. PMID: 18722174
14. We detected no confirmation of the recent association of variants in CTNNBL1 with obesity in a population of Central European ancestry PMID: 19228371
15. CTNNBL1 variants associated with body weight and height, and confer the risk of developing obesity PMID: 19245693

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HGNC: 15879

OMIM: 611537

KEGG: hsa:56259

STRING: 9606.ENSP00000355050

UniGene: Hs.472667