CYP3A7 Antibody

Datasheet

Code	CSB-PA006444LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA006444LA01HU at dilution of 1:100 Immunofluorescent analysis of HepG2 cells using CSB-PA006444LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CYP3A7 Polyclonal antibody

Uniprot No.

P24462

Target Names

CYP3A7

Alternative Names

Aryl hydrocarbon hydroxylase antibody; CP37 antibody; CP3A7_HUMAN antibody; CYP3A7 antibody; CYPIIIA7 antibody; Cytochrome P450 3A7 antibody; Cytochrome P450; family 3; subfamily A; polypeptide 7 antibody; Cytochrome P450; subfamily IIIA; polypeptide 7 antibody; Cytochrome P450-HFLA antibody; Flavoprotein linked monooxygenase antibody; Flavoprotein-linked monooxygenase antibody; Microsomal monooxygenase antibody; P 450(HFL33) antibody; P 450111A7 antibody; P450 HFLA antibody; Xenobiotic monooxygenase antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Cytochrome P450 3A7 protein (1-200AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The CYP3A7 Antibody (Product code: CSB-PA006444LA01HU) is Non-conjugated. For CYP3A7 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA006444LB01HU	CYP3A7 Antibody, HRP conjugated	ELISA
FITC	CSB-PA006444LC01HU	CYP3A7 Antibody, FITC conjugated
Biotin	CSB-PA006444LD01HU	CYP3A7 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

A cytochrome P450 monooxygenase involved in the metabolism of steroid hormones and vitamins during embryogenesis. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Metabolizes 3beta-hydroxyandrost-5-en-17-one (dehydroepiandrosterone, DHEA), a precursor in the biosynthesis of androgen and estrogen steroid hormones. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1), particularly D-ring hydroxylated estrone at the C16-alpha position. Mainly hydroxylates all trans-retinoic acid (atRA) to 4-hydroxyretinoate and may play a role in atRA clearance during fetal development. Also involved in the oxidative metabolism of xenobiotics including anticonvulsants.

Subcellular Location

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Protein Families

Cytochrome P450 family

Tissue Specificity

Expressed in fetal liver (at protein level).

Database Links

HGNC: 2640

OMIM: 605340

KEGG: hsa:100861540

STRING: 9606.ENSP00000337450

UniGene: Hs.111944

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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