Cleaved-MMP27 (Y99) Antibody

Code CSB-PA000055
Size US$100
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  • Western Blot analysis of COS7 cells using Cleaved-MMP-27 (Y99) Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
MMP27
Alternative Names
EC 3.4.24. antibody; Matrix metallopeptidase 27 antibody; Matrix metalloprotease 27 antibody; Matrix metalloproteinase 27 antibody; Matrix metalloproteinase-27 antibody; MMP 27 antibody; MMP-27 antibody; MMP27 antibody; MMP27_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Monkey
Immunogen
Synthesized peptide derived from the Internal region of Human MMP-27.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Matrix metalloproteinases degrade protein components of the extracellular matrix such as fibronectin, laminin, gelatins and/or collagens.
Gene References into Functions
  1. MMP-27 is expressed in a subset of endometrial macrophages related to menstruation and in ovarian and peritoneal endometriotic lesions. PMID: 24810263
  2. MMP-27 is efficiently retained within the ER due to its unique CTE, which does not lead to stable membrane insertion. This could represent a novel ER retention system PMID: 24548619
Subcellular Location
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein Families
Peptidase M10A family
Tissue Specificity
Expressed in B-cells. Expressed in a subset of endometrial macrophages related to menstruation and in ovarian and peritoneal endometriotic lesions (at protein level)(PubMed:24810263).
Database Links

HGNC: 14250

KEGG: hsa:64066

STRING: 9606.ENSP00000260229

UniGene: Hs.534479

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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