DAK Antibody

Datasheet

Code	CSB-PA006491GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q3LXA3

Target Names

TKFC

Alternative Names

ATP dependent dihydroxyacetone kinase antibody; Bifunctional ATP dependent dihydroxyacetone kinase/FAD AMP lyase (cyclizing) antibody; DAK antibody; DHA kinase antibody; Dha kinase/FMN cyclase antibody; DHAK_HUMAN antibody; Dihydroxyacetone kinase antibody; Dihydroxyacetone kinase 2 antibody; Dihydroxyacetone kinase 2 homolog (S. cerevisiae) antibody; Dihydroxyacetone kinase 2 homolog (yeast) antibody; FAD AMP lyase (cyclic FMN forming) antibody; FAD AMP lyase (cyclizing) antibody; FAD-AMP lyase (cyclic FMN forming) antibody; FAD-AMP lyase (cyclizing) antibody; FMN cyclase antibody; Glycerone kinase antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human DAK

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate. Represses IFIH1-mediated cellular antiviral response.

Gene References into Functions

The peptide fragment (m/z 520.3) of DAK is a promising biomarker to guide timing of antiviral treatment and to avoid liver biopsy in compensated chronic hepatitis B patients. PMID: 24289155
analysis of human triokinase/FMN cyclase reveals that kinase activity requires intact homodimers, but cyclase requires only a truncated, single domain subunit PMID: 24569995
Evidence supports that a single protein sustains both FMN cyclase and ATP-dependent Dha kinase activities, probably in a single active center PMID: 16289032
DAK, the physiological suppressor of cytoplasmic viral RNA sensor MDA5, specifically inhibits MDA5- but not RNA helicase RIG-I-mediated innate antiviral signaling. PMID: 17600090

Protein Families

Dihydroxyacetone kinase (DAK) family

Tissue Specificity

Detected in erythrocytes (at protein level).

Database Links

HGNC: 24552

OMIM: 615844

KEGG: hsa:26007

STRING: 9606.ENSP00000378360

UniGene: Hs.6278

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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