DAP3 Antibody

Code CSB-PA006497ESR2HU
Size US$166
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  • Western blot
    All lanes: 28S ribosomal protein S29, mitochondrial antibody at 10μg/ml
    Lane 1: Hela whole cell lysate
    Lane 2: 293T whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 46, 42 kDa
    Observed band size: 46 kDa

  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA006497ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DAP3 Polyclonal antibody
Uniprot No.
Target Names
DAP3
Alternative Names
28S ribosomal protein S29 antibody; 28S ribosomal protein S29 mitochondrial antibody; bMRP10 antibody; DAP 3 antibody; DAP-3 antibody; Dap3 antibody; Death associated protein 3 antibody; Death-associated protein 3 antibody; DKFZp686G12159 antibody; FLJ12817 antibody; Ionizing radiation resistance conferring protein antibody; MGC126058 antibody; MGC126059 antibody; Mitochondrial 28S ribosomal protein S29 antibody; mitochondrial antibody; MITOCHONDRIAL RIBOSOMAL PROTEIN S29 antibody; MRP S29 antibody; MRP-S29 antibody; MRPS29 antibody; OTTHUMP00000033480 antibody; OTTHUMP00000033481 antibody; PSD-95/SAP90-binding protein 3 antibody; RT29_HUMAN antibody; S29mt antibody; SAP90/PSD-95-associated protein 3 antibody; SAPAP3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human 28S ribosomal protein S29, mitochondrial protein (159-398AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Involved in mediating interferon-gamma-induced cell death.
Gene References into Functions
  1. DAP3 plays important roles in mitochondrial function and dynamics PMID: 26306039
  2. DAP3 silencing contributes to breast carcinogenesis. PMID: 25738636
  3. Knockdown of DAP3 expression promoted cell migration. PMID: 24300973
  4. Study demonstrates an inverse association between DAP3 mRNA levels and tumour stage and clinical outcome in breast cancer. PMID: 22287761
  5. identified a novel DAP3-binding protein termed death ligand signal enhancer (DELE); results demonstrated the biological significance of DELE for apoptosis signal mediated by death receptors PMID: 20563667
  6. show that interferon-beta promoter stimulator 1 (IPS-1) binds DAP3 and induces anoikis by caspase activation. PMID: 19644511
  7. Functional interaction between the pro-apoptotic DAP3 and the glucocorticoid receptor PMID: 12099703
  8. not involved in TRAIL-induced apoptosis PMID: 12359235
  9. DAP3 has a role in the molecular pathway that culminates in fragmented mitochondria PMID: 15175341
  10. DAP3 gene might be associated with the mechanisms responsible for adult bronchial asthma and contribute to airway inflammation and remodeling PMID: 15179560
  11. DAP3 has a role in anoikis signaling and in apoptosis induction caused by cell detachment PMID: 15302871
  12. High DAP3 expression is correlated with thymoma stage PMID: 15679048
  13. study investigated the phosphorylation status of ribosomal DAP3 and mapped the phosphorylation sites by tandem mass spectrometry PMID: 18227431
  14. Complex I and DAP3, hNOA1 may play a role in mitochondrial respiration and apoptosis. PMID: 19103604
  15. DAP3 may participate in mitochondrial maintenance and play a role in the balance between mitochondrial homoeostasis and tumourigenesis in thyroid oncocytic tumors. PMID: 19536094

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Subcellular Location
Mitochondrion.
Protein Families
Mitochondrion-specific ribosomal protein mS29 family
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 2673

OMIM: 602074

KEGG: hsa:7818

STRING: 9606.ENSP00000341692

UniGene: Hs.516746

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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