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DDX24 Antibody

Datasheet
Code CSB-PA050498
Size US$297
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Image
  • Immunohistochemistry analysis of paraffin-embedded human brain tissue using DDX24 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DDX24 Polyclonal antibody
Uniprot No.
Q9GZR7
Target Names
DDX24
Alternative Names
ATP dependent RNA helicase DDX24 antibody; ATP-dependent RNA helicase ddx24 antibody; DDX 24 antibody; ddx24 antibody; DDX24_HUMAN antibody; DEAD (Asp Glu Ala Asp) box polypeptide 24 antibody; DEAD box protein 24 antibody; DEAD/H (Asp Glu Ala Asp) box polypeptide 24 antibody; S. cerevisiae CHL1 like helicase antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human DDX24.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:50-1:100
Protocols
ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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DDX24 Antibodies

DDX24 Proteins

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Target Background

Function
ATP-dependent RNA helicase.
Gene References into Functions
  1. DDX24 is a negative regulator of p53 transcriptional activity.DDX24 inhibits p300 mediated acetylation of p53. PMID: 25867071
  2. depletion of DDX24 in cells impaired pre-rRNA processing and resulted both in abrogation of MDM2 function and in consequent p53 stabilization PMID: 24980433
  3. knockdown of a DEAD-box protein named DDX24 inhibits the packaging of HIV-1 RNA and thus diminishes viral infectivity. PMID: 18289627
Protein Families
DEAD box helicase family, DDX24/MAK5 subfamily
Tissue Specificity
Ubiquitous. Most abundant in heart and brain, but with lowest levels in thymus and small intestine.
Database Links

HGNC: 13266

OMIM: 606181

KEGG: hsa:57062

STRING: 9606.ENSP00000328690

UniGene: Hs.510328

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