DEPP1 Antibody, Biotin conjugated

Code CSB-PA865135LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DEPP1 Polyclonal antibody
Uniprot No.
Target Names
DEPP1
Alternative Names
Decidual protein induced by progesterone antibody; Depp antibody; DEPP_HUMAN antibody; Fasting-induced gene protein antibody; FIG antibody; Protein DEPP antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein DEPP1 protein (57-174AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Acts as a critical modulator of FOXO3-induced autophagy via increased cellular ROS.
Gene References into Functions
  1. Knockdown of DEPP prevented the primary and secondary reactive oxygen species wave during FOXO3 activation. PMID: 25261981
  2. C10orf10 expression is frequently decreased in breast cancer tissues and is associated with shorter survival times. PMID: 24936657
  3. DEPP is regulated at the level of transcription by FoxO in human vascular endothelial cells PMID: 21510935
  4. DEPP is a novel insulin-regulatory molecule expressed abundantly in insulin-sensitive tissues including white adipose tissue and liver. PMID: 19937567
  5. Expressed in endothelial cells of peripheral tissues, but not in atrial or ventricular endocardial cells of the heart, unexpected degree of molecular heterogeneity among arterial endothelial cells, up-regulated in subsets of endothelial cells. PMID: 15977181
  6. Depp modulates the effects of progesterone during decidualization and in the decidua by affecting gene expression. PMID: 16123073

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Subcellular Location
Cytoplasm. Peroxisome. Mitochondrion.
Tissue Specificity
Expressed in various tissues, including pancreas, placenta, ovary, testis and kidney.
Database Links

HGNC: 23355

OMIM: 611309

KEGG: hsa:11067

STRING: 9606.ENSP00000298295

UniGene: Hs.93675

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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